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Protein Overview: mec-2

General Information:
Name(s) found: mec-2 / CE04393 [WormBase]
Description(s) found:
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  • WBGene00003166 locus:mec-2 Mechanosensory protein 2 status:Confirmed UniProt:Q27433 protein_id:CCD83468.1 [WormBase]
  • gi|973212|gb|AAA87552.1| MEC-2 [NCBI NR]
  • gi|973210|gb|AAA87551.1| MEC-2 [NCBI NR]
  • gi|25153583|ref|NP_741797.1| MEChanosensory abnormality family member (mec-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|2493263|sp|Q27433.1|MEC2_CAEEL RecName: Full=Mechanosensory protein 2 [NCBI NR]
  • pir||S60260 stomatin-like protein - Caenorhabditis elegans [NCBI NR]
  • gi|1585780|prf||2201490A stomatin-like protein [NCBI NR]
  • gi|1086680|gb|AAA82333.1| Mechanosensory abnormality protein 2, isoform a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • Mechanosensory protein 2 OS=Caenorhabditis elegans GN=mec-2 PE=1 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE04393 WBGene00003166 locus:mec-2 status:Confirmed SW:Q27433 protein_id:AAA82333.1 [wormpep150.fasta]
  • 04393 WBGene00003166 locus:mec-2 status:Confirmed SW:Q27433 protein_id:AAA82333.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • MEChanosensory abnormality MEC-2, stomatin-like protein required for mechanosensation (51.9 kD) (mec-2) [Caenorhabditis elegans]gi|1086680|gb|AAA82333.1| Mechanosensory abnormality protein 2, isoform a [Caenorhabditis elegans]gi|2133486|pir||S60260 stom [nrdb_11152004_Chlamydomonas]
  • locus:mec-2 status:Confirmed SW:Q27433 protein_id:AAA82333.1 [wormpep115.fasta.reversed]
  • CE04393 locus:mec-2 status:Confirmed [wormpep80.hongbin]
  • CE04393 WBGene00003166 locus:mec-2 status:Confirmed UniProt:Q27433 protein_id:AAA82333.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE04393 WBGene00003166 locus:mec-2 status:Confirmed UniProt:Q27433 protein_id:AAA82333.1| [wormORF-contam.fasta]
  • MEChanosensory abnormality family member (mec-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Mechanosensory abnormality protein 2, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • MEC-2 [nr-271106-contam.fasta]
  • stomatin-like protein [nr-271106-contam.fasta]
  • Mechanosensory protein 2 [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE04393 WBGene00003166 locus:mec-2 status:Confirmed UniProt:Q27433 protein_id:CCD83468.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE04393 WBGene00003166 locus:mec-2 status:Confirmed UniProt:Q27433 protein_id:CCD83468.1 Mechanosensory protein 2 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 481 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    neuron projection [IDALink to PubMed article]
    Biological Process: mechanosensory behavior [IMPLink to PubMed article]
    response to mechanical stimulus [IMPLink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article]
    peptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATMSSARN SVVSLSSNGS VKVETRLVSN ERSSSIQQEG AMLPSSSSKD DDLLSTSSDE  60
   61 VENMATRTLQ QLEESTSIIS ANSDDDSVKK EKQAEKDVEK GNGKEEKANI QNEFGVCGWI 120
  121 LTILSYLLIF FTLPISACMC IKVVQEYERA VIFRLGRLMP GGAKGPGIFF IVPCIDTYRK 180
  181 VDLRVLSFEV PPQEILSKDS VTVAVDAVVY FRISNATISV TNVEDAARST KLLAQTTLRN 240
  241 ILGTKTLAEM LSDREAISHQ MQTTLDEATE PWGVKVERVE VKDVRLPVQL QRAMAAEAEA 300
  301 AREARAKVIV AEGEQKASRA LKEAAEVIAE SPSALQLRYL QTLNSISAEK NSTIIFPFPI 360
  361 DLLSAFLQRT PPKVEEPPSL PKKIRSCCLY KYPDWVQGMV GSEGGGGHGH SHGGGGGGLG 420
  421 SSQGAFHPSQ AGSGPSTTTT SGRPLLRSMR EAQFHSAAPP ISAPNQSQTS VSQLDPALLI 480
  481 R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..144] MSA 1.752975 View MSA. No confident structure predictions are available.
    2 View Details [145..374] PSI-BLAST 11.221849 Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
    3 View Details [375..481] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.67282155252301 bayes_pls_golite062009
  • structural molecule activity
    		•  0.834496144484266 bayes_pls_golite062009
  • protein binding
    		•  0.769979871341236 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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