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View Structure Prediction Details

Protein: mec-2
Organism: Caenorhabditis elegans
Length: 481 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mec-2.

Description E-value Query
Range
Subject
Range
mec-2 - status:Confirmed UniProt:Q8MQ74 protein_id:AAM54192.1
351.0 [0..1] [370..1]

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Predicted Domain #1
Region A:
Residues: [1-144]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATMSSARN SVVSLSSNGS VKVETRLVSN ERSSSIQQEG AMLPSSSSKD DDLLSTSSDE  60
   61 VENMATRTLQ QLEESTSIIS ANSDDDSVKK EKQAEKDVEK GNGKEEKANI QNEFGVCGWI 120
  121 LTILSYLLIF FTLPISACMC IKVV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [145-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEYERAVIFR LGRLMPGGAK GPGIFFIVPC IDTYRKVDLR VLSFEVPPQE ILSKDSVTVA  60
   61 VDAVVYFRIS NATISVTNVE DAARSTKLLA QTTLRNILGT KTLAEMLSDR EAISHQMQTT 120
  121 LDEATEPWGV KVERVEVKDV RLPVQLQRAM AAEAEAAREA RAKVIVAEGE QKASRALKEA 180
  181 AEVIAESPSA LQLRYLQTLN SISAEKNSTI IFPFPIDLLS AFLQRTPPKV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.221849
Match: 1winA
Description: Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.67282155252301 bayes_pls_golite062009
structural molecule activity 0.834496144484266 bayes_pls_golite062009
protein binding 0.769979871341236 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [375-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEPPSLPKKI RSCCLYKYPD WVQGMVGSEG GGGHGHSHGG GGGGLGSSQG AFHPSQAGSG  60
   61 PSTTTTSGRP LLRSMREAQF HSAAPPISAP NQSQTSVSQL DPALLIR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle