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Protein Overview: asp-4

General Information:
Name(s) found: asp-4 / CE03567 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00000217 locus:asp-4 status:Confirmed UniProt:Q21966 protein_id:CAA90633.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 444 amino acids

    Gene Ontology:
    Cellular Component: lysosome [ICLink to PubMed article]
    Biological Process: cell death [IMPLink to PubMed article]
    proteolysis [IEALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: aspartic-type endopeptidase activity [IEALink to PubMed article][ISSLink to PubMed article]
    pepsin A activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRCILLLLG ALLLVQGLHV HKRQQKLRTV SLKKQPTLRE TLLQAGSFET FAKHRHGYKK  60
   61 YLKTNGNHHF DKYQALNVEG EIDELLRNYM DAQYFGTISI GTPAQNFTVI FDTGSSNLWI 120
  121 PSKKCPFYDI ACMLHHRYDS KSSSTYKEDG RKMAIQYGTG SMKGFISKDS VCVAGVCAED 180
  181 QPFAEATSEP GITFVAAKFD GILGMAYPEI AVLGVQPVFN TLFEQKKVPS NLFSFWLNRN 240
  241 PDSEIGGEIT FGGIDSRRYV EPITYVPVTR KGYWQFKMDK VVGSGVLGCS NGCQAIADTG 300
  301 TSLIAGPKAQ IEAIQNFIGA EPLIKGEYMI SCDKVPTLPP VSFVIGGQEF SLKGEDYVLK 360
  361 VSQGGKTICL SGFMGIDLPE RVGELWILGD VFIGRYYSVF DFDQNRVGFA QAKTADGRPV 420
  421 DPAPRPFRSV FDNESEESME QDDE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..444] PSI-BLAST 92.0 REFINED STRUCTURE OF PORCINE PEPSINOGEN AT 1.8 ANGSTROMS RESOLUTION

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • aspartic-type endopeptidase activity
    		•  7.9145950161796 bayes_pls_golite062009
  • aspartic-type peptidase activity
    		•  7.9145950161796 bayes_pls_golite062009
  • peptidase activity
    		•  5.78181196721293 bayes_pls_golite062009
  • endopeptidase activity
    		•  5.4888481808613 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  5.39972232367526 bayes_pls_golite062009
  • hydrolase activity
    		•  4.34796304893506 bayes_pls_golite062009
  • catalytic activity
    		•  1.54514410489082 bayes_pls_golite062009
  • protein binding
    		•  1.24436201877985 bayes_pls_golite062009
  • binding
    		•  1.10054369202721 bayes_pls_golite062009
  • receptor binding
    		•  1.06854757360057 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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