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Protein Overview: dhs-6

General Information:
Name(s) found: dhs-6 / CE02490 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00000970 locus:dhs-6 status:Confirmed UniProt:Q09979 protein_id:CCD64960.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 418 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: estrogen biosynthetic process [IEALink to PubMed article]
    poly-hydroxybutyrate biosynthetic process [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    fatty acid biosynthetic process [IEALink to PubMed article]
    Molecular Function: estradiol 17-beta-dehydrogenase activity [IEALink to PubMed article]
    3-oxoacyl-[acyl-carrier-protein] reductase activity [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    3-hydroxybutyrate dehydrogenase activity [IEALink to PubMed article]
    acetoacetyl-CoA reductase activity [IEALink to PubMed article]
    2-deoxy-D-gluconate 3-dehydrogenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNTGKFVGR TVLITGASRG IGKEIALKLA KDGANIVVAA KTATAHPKLP GTIYSAAEEI  60
   61 EKAGGKALPC IVDVRDEASV KASVEEAVKK FGGIDILINN ASAISLTDTE NTEMKRYDLM 120
  121 HSINTRGTFL MTKTCLPYLK SGKNPHVLNI SPPLLMETRW FANHVAYTMA KYGMSMCVLG 180
  181 QHEEFRPHGI AVNALWPLTA IWTAAMEMLS DKGGEAGSRK PSIMADAAYA VLSKNSKDFT 240
  241 GNFCIDEDIL KAEGVTDFDR YACVPDAPLM PDFFIPAGTY DHKFSSGAQI GKKNKTHEAG 300
  301 VVEEEIKQIF TSAKRLLNAD IVKKTGFVYE FLLKDPTTKS ERIITLDLKN GEGALTDKKA 360
  361 SGKADVKFTL APEHFAPLFT GKLRPTTALM TKKLQISGDM PGAMKLESLL RKFTEGKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..294] PSI-BLAST 54.0 Crystal structure of peroxisomal trans 2-enoyl CoA reductase
    2 View Details [295..418] PSI-BLAST 31.0 SCP2-like domain of MFE-2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.69771604880532 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  1.23679054027553 bayes_pls_golite062009
  • 3-oxoacyl-[acyl-carrier-protein] reductase activity
    		•  0.604742541607263 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.418775403210681 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.32207755075663 bayes_pls_golite062009
    2
    Term Confidence Notes
  • sterol carrier protein X-related thiolase activity
    		•  1.71600951762874 bayes_pls_golite062009
  • sterol binding
    		•  0.77874943487633 bayes_pls_golite062009
  • lipid binding
    		•  0.612082389575099 bayes_pls_golite062009
  • catalytic activity
    		•  0.334051377480817 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle