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View Structure Prediction Details

Protein: dhs-6
Organism: Caenorhabditis elegans
Length: 418 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dhs-6.

Description E-value Query
Range
Subject
Range
gi|7496230 - gi|7496230|pir||T34105 hypothetical protein C17G10.8 - Caenorhabditis elegans
371.0 [0..1] [418..521]

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Predicted Domain #1
Region A:
Residues: [1-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNTGKFVGR TVLITGASRG IGKEIALKLA KDGANIVVAA KTATAHPKLP GTIYSAAEEI  60
   61 EKAGGKALPC IVDVRDEASV KASVEEAVKK FGGIDILINN ASAISLTDTE NTEMKRYDLM 120
  121 HSINTRGTFL MTKTCLPYLK SGKNPHVLNI SPPLLMETRW FANHVAYTMA KYGMSMCVLG 180
  181 QHEEFRPHGI AVNALWPLTA IWTAAMEMLS DKGGEAGSRK PSIMADAAYA VLSKNSKDFT 240
  241 GNFCIDEDIL KAEGVTDFDR YACVPDAPLM PDFFIPAGTY DHKFSSGAQI GKKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.0
Match: 1yxmA
Description: Crystal structure of peroxisomal trans 2-enoyl CoA reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity 1.69771604880532 bayes_pls_golite062009
fatty acid synthase activity 1.23679054027553 bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity 0.604742541607263 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.418775403210681 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.32207755075663 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [295-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTHEAGVVEE EIKQIFTSAK RLLNADIVKK TGFVYEFLLK DPTTKSERII TLDLKNGEGA  60
   61 LTDKKASGKA DVKFTLAPEH FAPLFTGKLR PTTALMTKKL QISGDMPGAM KLESLLRKFT 120
  121 EGKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.0
Match: 1iktA
Description: SCP2-like domain of MFE-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sterol carrier protein X-related thiolase activity 1.71600951762874 bayes_pls_golite062009
sterol binding 0.77874943487633 bayes_pls_golite062009
lipid binding 0.612082389575099 bayes_pls_golite062009
catalytic activity 0.334051377480817 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle