YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: ldh-1

General Information:
Name(s) found: ldh-1 / CE02181 [WormBase]
Description(s) found:
Found 24 descriptions.
SHOW ALL
  • WBGene00002262 locus:ldh-1 L-lactate dehydrogenase status:Confirmed UniProt:Q27888 protein_id:CAA88944.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 333 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: malate metabolic process [IEALink to PubMed article]
    cellular carbohydrate metabolic process [IEALink to PubMed article]
    glycolysis [IEALink to PubMed article]
    tricarboxylic acid cycle intermediate metabolic process [IEALink to PubMed article]
    Molecular Function: L-malate dehydrogenase activity [IEALink to PubMed article]
    malate dehydrogenase activity [IEALink to PubMed article]
    L-lactate dehydrogenase activity [IEALink to PubMed article]
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTIKEVFA EIAAPVENSH GKVTVVGVGQ VGMACAYSIL QQNLANELCL VDVVADKLKG  60
   61 EMMDLQHGLA FTRHCTVKAD TDYSITAGSK LCVVTAGARQ REGETRLSLV QRNVEIFKGI 120
  121 IPQLVKYSPD TCILVVSNPV DVLTYVTWKL SGLPRERVFG SGTNLDSARF RFLLSEKLNI 180
  181 APSSCHGWII GEHGDSSVAV WSGVNVAGVT LHEIKPDIGE KTDNEHWEAE IHKKVVDSAY 240
  241 EIIKLKGYTS WAIGLSVAKI AQGIFSNSRN VFALSTNVKG FHGINDDVYL SLPVVLGSAG 300
  301 LTHVVKQQLT EAEVQKLHNS AKALLEVQNG IVM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..333] PSI-BLAST 104.0 Lactate dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • L-lactate dehydrogenase activity
    		•  2.59062377380589 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  1.27032644348698 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  1.16811519855038 bayes_pls_golite062009
  • binding
    		•  0.982999356179965 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.9367410227151 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.74536049628503 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  0.729242797855749 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  0.714637370305282 bayes_pls_golite062009
  • DNA binding
    		•  0.525227236870065 bayes_pls_golite062009
  • protein binding
    		•  0.507836099271263 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.459537641913493 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.418775403210681 bayes_pls_golite062009
  • coenzyme binding
    		•  0.35922330382799 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.32207755075663 bayes_pls_golite062009
  • 3-oxoacyl-[acyl-carrier-protein] reductase activity
    		•  0.192594057004213 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.177044638410302 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.0433763403499039 bayes_pls_golite062009
  • signal transducer activity
    		•  0.0433763403499039 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle