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Protein Overview: crn-5

General Information:
Name(s) found: crn-5 / CE02146 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00000798 locus:crn-5 status:Confirmed UniProt:G5EG59 protein_id:CAA90109.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 214 amino acids

    Gene Ontology:
    Cellular Component: exosome (RNase complex) [IEALink to PubMed article][TASLink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed article]
    DNA fragmentation involved in apoptosis [IGILink to PubMed article][IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    RNA processing [IEALink to PubMed article][TASLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: 3'-5' exonuclease activity [ISSLink to PubMed article]
    3'-5'-exoribonuclease activity [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]
    exoribonuclease activity, producing 5'-phosphomonoesters [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGRLREMRC ELSFLKNADG SACFSQGATC IWASCSGPGD VHASKASDEA MTLDISYRAN  60
   61 CGDNKFNVLN NIIHSTLSNA INLELFPHTT ISVTVHGIQD DGSMGAVAIN GACFALLDNG 120
  121 MPFETVFCGV LIVRVKDELI IDPTAKQEAA STGRVLFSVC KGSDGHPEVC AMDAIGHWDF 180
  181 IQLEAAWSLA QPSASAIFDF YKTVMKRKLS VDEQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..214] PSI-BLAST 54.522879 Archaeal exosome core

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • exoribonuclease activity
    		•  7.55877202113513 bayes_pls_golite062009
  • ribonuclease activity
    		•  7.54644729272203 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  7.5310318714913 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  6.46930372693262 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  5.06256868878098 bayes_pls_golite062009
  • exonuclease activity
    		•  4.6643790818023 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  4.29895100594643 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.86434572018929 bayes_pls_golite062009
  • RNA binding
    		•  2.05527376734941 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.90115575554186 bayes_pls_golite062009
  • structural molecule activity
    		•  1.69321127364043 bayes_pls_golite062009
  • hydrolase activity
    		•  1.55476709794855 bayes_pls_golite062009
  • binding
    		•  1.3018457178158 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.20748032530392 bayes_pls_golite062009
  • mRNA binding
    		•  1.17402119891853 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.05662964529454 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • DNA binding
    		•  0.828609700556836 bayes_pls_golite062009
  • nuclease activity
    		•  0.69721312877891 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.51810239718467 bayes_pls_golite062009
  • tRNA-specific ribonuclease activity
    		•  0.383567539949931 bayes_pls_golite062009
  • deacetylase activity
    		•  0.2046781383773 bayes_pls_golite062009
  • protein binding
    		•  0.0913090112555771 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0287026367466632 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle