YRC Public Data Repository - Protein Structure Prediction

Protein:	crn-5
Organism:	Caenorhabditis elegans
Length:	214 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for crn-5.

Description	E-value	Query Range	Subject Range
PNP_CARHZ - Polyribonucleotide nucleotidyltransferase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 ...	229.0	[0..3]	[210..333]
gi\|107104436 - gi\|107104436\|ref\|ZP_01368354.1\| hypothetical protein PaerPA_01005513 [Pseudomonas aeruginosa PACS2]	228.0	[0..2]	[207..9]
RNPH_PSEA7 - Ribonuclease PH OS=Pseudomonas aeruginosa (strain PA7) GN=rph PE=3 SV=1	228.0	[0..2]	[207..9]
PNP_IDILO - Polyribonucleotide nucleotidyltransferase OS=Idiomarina loihiensis GN=pnp PE=3 SV=1 PNP_IDILO - Polyribonucleotide nucleotidyltransferase OS=Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 ...	227.0	[0..2]	[210..320]
gi\|94492192, gi\|... - gi\|94492192\|ref\|ZP_01299400.1\| hypothetical protein CburD_01000522 [Coxiella burnetii Dugway 7E9-12]... PNP_COXBR - Polyribonucleotide nucleotidyltransferase OS=Coxiella burnetii (strain RSA 331 / Henzerling II) GN=p... PNP_COXBU - Polyribonucleotide nucleotidyltransferase OS=Coxiella burnetii (strain RSA 493 / Nine Mile phase I) ... PNP_COXBU - Polyribonucleotide nucleotidyltransferase OS=Coxiella burnetii GN=pnp PE=3 SV=1 PNP_COXBN - Polyribonucleotide nucleotidyltransferase OS=Coxiella burnetii (strain Dugway 5J108-111) GN=pnp PE=3...	227.0	[0..5]	[211..327]
RNPH_PSEA8 - Ribonuclease PH OS=Pseudomonas aeruginosa (strain LESB58) GN=rph PE=3 SV=1 gi\|254237972, gi... - gi\|84317970\|ref\|ZP_00966404.1\| COG0689: RNase PH [Pseudomonas aeruginosa C3719], gi\|254237972\|ref\|ZP... gi\|254243780, gi... - gi\|84323960\|ref\|ZP_00972025.1\| COG0689: RNase PH [Pseudomonas aeruginosa 2192], gi\|254243780\|ref\|ZP_... RNPH_PSEAB - Ribonuclease PH OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=rph PE=3 SV=1 RNPH_PSEAE - Ribonuclease PH OS=Pseudomonas aeruginosa GN=rph PE=1 SV=2 RNPH_PSEAE - Ribonuclease PH OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=r...	227.0	[0..2]	[207..9]
PNP_CALS4 - Polyribonucleotide nucleotidyltransferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (str... PNP_THETN - Polyribonucleotide nucleotidyltransferase OS=Thermoanaerobacter tengcongensis GN=pnp PE=3 SV=1	226.0	[0..3]	[210..320]
gi\|49082078 - gi\|49082078\|gb\|AAT50439.1\| PA5334 [synthetic construct]	225.0	[0..2]	[207..9]
gi\|85693163, gi\|... - gi\|85712994\|ref\|ZP_01044032.1\| Polynucleotide phosphorylase [Idiomarina baltica OS145], gi\|85693163\|...	225.0	[0..2]	[209..320]
gi\|69153014, gi\|... - gi\|69935526\|ref\|ZP_00630462.1\| 3' exoribonuclease:RNA binding S1:KH, type 1 [Paracoccus denitrifican...	225.0	[0..5]	[207..348]

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Predicted Domain #1

Region A:
Residues: [1-214]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGRLREMRC ELSFLKNADG SACFSQGATC IWASCSGPGD VHASKASDEA MTLDISYRAN  60
   61 CGDNKFNVLN NIIHSTLSNA INLELFPHTT ISVTVHGIQD DGSMGAVAIN GACFALLDNG 120
  121 MPFETVFCGV LIVRVKDELI IDPTAKQEAA STGRVLFSVC KGSDGHPEVC AMDAIGHWDF 180
  181 IQLEAAWSLA QPSASAIFDF YKTVMKRKLS VDEQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.522879
Match:	2ba0F
Description:	Archaeal exosome core
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
exoribonuclease activity	7.55877202113513	bayes_pls_golite062009
ribonuclease activity	7.54644729272203	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	7.5310318714913	bayes_pls_golite062009
3'-5'-exoribonuclease activity	6.46930372693262	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	5.06256868878098	bayes_pls_golite062009
exonuclease activity	4.6643790818023	bayes_pls_golite062009
3'-5' exonuclease activity	4.29895100594643	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.86434572018929	bayes_pls_golite062009
RNA binding	2.05527376734941	bayes_pls_golite062009
structural constituent of ribosome	1.90115575554186	bayes_pls_golite062009
structural molecule activity	1.69321127364043	bayes_pls_golite062009
hydrolase activity	1.55476709794855	bayes_pls_golite062009
binding	1.3018457178158	bayes_pls_golite062009
transcription regulator activity	1.20748032530392	bayes_pls_golite062009
mRNA binding	1.17402119891853	bayes_pls_golite062009
nucleic acid binding	1.05662964529454	bayes_pls_golite062009
catalytic activity	0.878454819018611	bayes_pls_golite062009
DNA binding	0.828609700556836	bayes_pls_golite062009
nuclease activity	0.69721312877891	bayes_pls_golite062009
carbohydrate kinase activity	0.51810239718467	bayes_pls_golite062009
tRNA-specific ribonuclease activity	0.383567539949931	bayes_pls_golite062009
deacetylase activity	0.2046781383773	bayes_pls_golite062009
protein binding	0.0913090112555771	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.0287026367466632	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: