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Protein Overview: unc-4

General Information:
Name(s) found: unc-4 / CE01560 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00006744 locus:unc-4 Homeobox protein unc-4 status:Partially_confirmed UniProt:P29506 protein_id:CAA87368.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 252 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    axon [IDALink to PubMed article]
    Biological Process: synapse assembly [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    locomotion [IMPLink to PubMed article]
    regulation of axonogenesis [IMPLink to PubMed article]
    regulation of synapse structure and activity [IMPLink to PubMed article]
    neuroblast fate determination [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    regulation of transcription [ISSLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article][ISSLink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIGALHACVD AEPKIINDIW ADFWKSQINS VLLNPSDGSE TYLASDNGKS TSSREQSTSP  60
   61 DDDNLLMNED DGIALEDDND TGESAAKRRR TRTNFSGWQL EELESAFEAS HYPDVFMREA 120
  121 LAMRLDLLES RVQVWFQNRR AKWRKREQNR NGSSEIKKDD GEQMETKALP TFPFSIDSIL 180
  181 AVSRVPRGRR PNAKYPRVQA CKNLSPFMIP LFPITQPGGN VIREKSPPLP TQQSQIVATN 240
  241 ALTTVAELLK SV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] PSI-BLAST 25.69897 Paired protein
    2 View Details [153..252] MSA 11.156997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.51452285155271 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.41271657675151 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.26183812259792 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91962622287073 bayes_pls_golite062009
  • transcription activator activity
    		•  1.77700860354597 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.14886080629275 bayes_pls_golite062009
  • chromatin binding
    		•  1.04132983826241 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • protein binding
    		•  0.830419844171551 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.25931464844298 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle