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Protein Overview: tbp-1

General Information:
Name(s) found: tbp-1 / CE01408 [WormBase]
Description(s) found:
Found 25 descriptions.
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  • WBGene00006542 locus:tbp-1 TATA-box-binding protein status:Confirmed UniProt:P32085 protein_id:CCD69071.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 340 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    transcription factor TFIID complex [IEALink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    transcription initiation from RNA polymerase II promoter [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    RNA polymerase II transcription factor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLNSPAVSM LGGDTPAHGG PNSVLGGQGP SSILTGHGPN SVMGPNSILG PGSVLNPQSI  60
   61 QPMQSQQMHS LQGSSMQMHS HLANSNLNLN INPASVGPDR NPGSVMHHNL DINPPSVAYQ 120
  121 NLTVPMTPLA YSVYDRDALT HQAPASNIAA TMVPATPASQ LDIPMPALQN IVSTVNLGVQ 180
  181 LDLKKIALHA RNAEYNPKRF AAVIMRIREP RTTALIFSSG KMVCTGAKSE EASRLAARKY 240
  241 ARIVQKLGFQ AKFTEFMVQN MVGSCDVRFP IQLEGLCITH SQFSTYEPEL FPGLIYRMVK 300
  301 PRVVLLIFVS GKVVITGAKT KRDIDEAFGQ IYPILKGFKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..113] PSI-BLAST 3.69897 Sec24
    2 View Details [114..340] PSI-BLAST 88.69897 Structure of a Yeast TFIIA/TBP/TATA-box DNA Complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  10.1927670598446 bayes_pls_golite062009
  • RNA polymerase III transcription factor activity
    		•  8.4318102330583 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.66773099672992 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.97397050058114 bayes_pls_golite062009
  • DNA binding
    		•  3.93251147843671 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.82919607287537 bayes_pls_golite062009
  • RNA polymerase I transcription factor activity
    		•  3.24777019705869 bayes_pls_golite062009
  • binding
    		•  2.72886792846471 bayes_pls_golite062009
  • transcription factor activity
    		•  2.38288562794802 bayes_pls_golite062009
  • protein binding
    		•  1.96605926404517 bayes_pls_golite062009
  • transcription factor binding
    		•  1.86204668268867 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.59579825271822 bayes_pls_golite062009
  • transcription activator activity
    		•  1.5285505684695 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.16858275919592 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.312991469396539 bayes_pls_golite062009
  • chromatin binding
    		•  0.107733889697044 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.56

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle