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View Structure Prediction Details

Protein: tbp-1
Organism: Caenorhabditis elegans
Length: 340 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tbp-1.

Description E-value Query
Range
Subject
Range
TBPL2_XENLA - TATA box-binding protein-like protein 2 OS=Xenopus laevis GN=tbpl2 PE=2 SV=1
362.0 [0..41] [340..18]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLNSPAVSM LGGDTPAHGG PNSVLGGQGP SSILTGHGPN SVMGPNSILG PGSVLNPQSI  60
   61 QPMQSQQMHS LQGSSMQMHS HLANSNLNLN INPASVGPDR NPGSVMHHNL DIN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [114-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPSVAYQNLT VPMTPLAYSV YDRDALTHQA PASNIAATMV PATPASQLDI PMPALQNIVS  60
   61 TVNLGVQLDL KKIALHARNA EYNPKRFAAV IMRIREPRTT ALIFSSGKMV CTGAKSEEAS 120
  121 RLAARKYARI VQKLGFQAKF TEFMVQNMVG SCDVRFPIQL EGLCITHSQF STYEPELFPG 180
  181 LIYRMVKPRV VLLIFVSGKV VITGAKTKRD IDEAFGQIYP ILKGFKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 88.69897
Match: 1rm1A
Description: Structure of a Yeast TFIIA/TBP/TATA-box DNA Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 10.1927670598446 bayes_pls_golite062009
RNA polymerase III transcription factor activity 8.4318102330583 bayes_pls_golite062009
transcription regulator activity 4.66773099672992 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.97397050058114 bayes_pls_golite062009
DNA binding 3.93251147843671 bayes_pls_golite062009
nucleic acid binding 3.82919607287537 bayes_pls_golite062009
RNA polymerase I transcription factor activity 3.24777019705869 bayes_pls_golite062009
binding 2.72886792846471 bayes_pls_golite062009
transcription factor activity 2.38288562794802 bayes_pls_golite062009
protein binding 1.96605926404517 bayes_pls_golite062009
transcription factor binding 1.86204668268867 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.59579825271822 bayes_pls_golite062009
transcription activator activity 1.5285505684695 bayes_pls_golite062009
sequence-specific DNA binding 1.16858275919592 bayes_pls_golite062009
transcription coactivator activity 0.312991469396539 bayes_pls_golite062009
chromatin binding 0.107733889697044 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle