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Protein Overview: aqp-1

General Information:
Name(s) found: aqp-1 / CE01275 [WormBase]
Description(s) found:
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  • WBGene00000169 locus:aqp-1 status:Confirmed UniProt:Q8IG23 protein_id:CCD66277.1 [WormBase]
  • pir||T16231 hypothetical protein F32A5.5 - Caenorhabditis elegans [NCBI NR]
  • gi|32564052|ref|NP_871933.1| AQuaPorin or aquaglyceroporin related family member (aqp-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|24943015|gb|AAN65321.1| Aquaporin or aquaglyceroporin related protein 1, isoform b [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE01275 WBGene00000169 locus:aqp-1 status:Confirmed TR:Q8IG23 protein_id:AAN65321.1 [wormpep150.fasta]
  • 01275 WBGene00000169 locus:aqp-1 status:Confirmed TR:Q8IG23 protein_id:AAN65321.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • MIP family (32.5 kD) (2H526) [Caenorhabditis elegans]gi|24943015|gb|AAN65321.1| Aquaporin or aquaglyceroporin related protein 1, isoform b [Caenorhabditis elegans]gi|7444134|pir||T16231 hypothetical protein F32A5.5 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • status:Confirmed TR:Q8IG23 protein_id:AAN65321.1 [wormpep115.fasta.reversed]
  • CE01275 WBGene00000169 locus:aqp-1 status:Confirmed UniProt:Q8IG23_CAEEL protein_id:AAN65321.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE01275 WBGene00000169 locus:aqp-1 status:Confirmed UniProt:Q8IG23_CAEEL protein_id:AAN65321.1| [wormORF-contam.fasta]
  • Aquaporin or aquaglyceroporin related protein 1, isoform b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • AQuaPorin or aquaglyceroporin related family member (aqp-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE01275 WBGene00000169 locus:aqp-1 status:Confirmed UniProt:Q8IG23 protein_id:AAN65321.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE01275 WBGene00000169 locus:aqp-1 status:Confirmed UniProt:Q8IG23 protein_id:CCD66277.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of Q19949, AQuaPorin or aquaglyceroporin related OS=Caenorhabditis elegans GN=aqp-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 295 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: determination of adult lifespan [IMPLink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAEEDTLPE RLRFHGVHTN ILARNLIAEF FGTFLLCFIG LSIVFQFHAG GGKTTEWIGV  60
   61 NIGWGFAIMF AVMATARMSG GHLNPAVSLL LWSLGHLKLA WVPLYAIAQT AGAFVASLGM 120
  121 YSYYYEQFNA FDGGNRTILG ATGTAGCFAS YPSPNLGVWG PYIDQCVGTG VLAYFLCVVI 180
  181 DERNQIPKIW HPMFFGFLVM MIGTGFGMNI GYPINPARDL GPRLFSYFIY GPGVFHSPYP 240
  241 NYWLAPAIAP FVGALVGGWF YHFSLGMHNP DIEEADDIFV QQPPKSVEQQ KLLQA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..295] PSI-BLAST 56.69897 Glycerol uptake facilitator protein GlpF

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • water transmembrane transporter activity
    		•  10.3414560257964 bayes_pls_golite062009
  • water channel activity
    		•  10.2169080705067 bayes_pls_golite062009
  • amide transmembrane transporter activity
    		•  8.22334514934522 bayes_pls_golite062009
  • urea channel activity
    		•  8.22334514934522 bayes_pls_golite062009
  • urea transmembrane transporter activity
    		•  8.22334514934522 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  6.84984722645819 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  6.65010837320829 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  6.65010837320829 bayes_pls_golite062009
  • transporter activity
    		•  5.23077472964938 bayes_pls_golite062009
  • pyrimidine transmembrane transporter activity
    		•  5.22583580934587 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  5.0695479460357 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  5.06520190871345 bayes_pls_golite062009
  • channel activity
    		•  5.06054430984045 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  5.06054430984045 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  4.83314424546299 bayes_pls_golite062009
  • glycerol channel activity
    		•  4.65460547189577 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.82456291801633 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity
    		•  1.9587945604969 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  1.57078059027065 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  1.57017437613762 bayes_pls_golite062009
  • nucleobase transmembrane transporter activity
    		•  1.34339324336864 bayes_pls_golite062009
  • purine transmembrane transporter activity
    		•  1.34339324336864 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  1.16825682067665 bayes_pls_golite062009
  • binding
    		•  1.07947257986943 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.516648340085278 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.315342449421593 bayes_pls_golite062009
  • protein binding
    		•  0.279304481542405 bayes_pls_golite062009
  • structural molecule activity
    		•  0.180281371901848 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.141210715822635 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0368961725897963 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle