YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: nhr-10

General Information:
Name(s) found: nhr-10 / CE00815 [WormBase]
Description(s) found:
Found 21 descriptions.
SHOW ALL
  • WBGene00003609 locus:nhr-10 Nuclear hormone receptor family member nhr-10 status:Confirmed UniProt:P41999 protein_id:CCD61604.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 395 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGGGPSSNN SSQPEEVCLV CSDISTGYHY GVPSCNGCKT FFRRTIMKNQ TFSCQFQGKC  60
   61 PVDKSIRCAC RHCRFEKCLQ VGMDRNAIQQ NRDPIGYTKR TRRYPPIKKV EASDECSPAM 120
  121 VSENDRSEDN FLTLLSSTEQ KCCALRLAEY MPSRTLIEAV VSDCLLTDEV FMAEHAILSP 180
  181 RHRVTSLRFA NQSDYHYWHE RDWFVMIEWA KTLPVFQSLP FTDKLALLRH SAITYPSLVH 240
  241 VFNSPDHGLD TIVFPDGAYF DRTPEPTRPL GFNKKKYQML DQLLKPMRSM EIDMTEFAAF 300
  301 KAIFFLNPDA DDVDSNAKKT LSDGRSAITN ALYRYMVKKK GAEDAGDRFG RLLLLGTVLA 360
  361 TMAVEMKEAV LVADFFDQIQ FSTFAKQLLF GIKTE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..113] PSI-BLAST 21.30103 Steroid hormone receptor Err2
    2 View Details [114..395] PSI-BLAST 44.69897 Crystal structure of the agonist-bound ligand-binding domain of Biomphalaria glabrata RXR

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  4.00967542385368 bayes_pls_golite062009
  • DNA binding
    		•  3.60745514727532 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.47256374293954 bayes_pls_golite062009
  • binding
    		•  2.96409924710655 bayes_pls_golite062009
  • transcription activator activity
    		•  2.9532663930699 bayes_pls_golite062009
  • transcription factor activity
    		•  2.90769972671972 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.72967350701574 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.55186574506963 bayes_pls_golite062009
  • protein binding
    		•  2.44501340584871 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.40923942043513 bayes_pls_golite062009
  • steroid hormone receptor binding
    		•  2.19264900659739 bayes_pls_golite062009
  • androgen receptor binding
    		•  1.92232680714675 bayes_pls_golite062009
  • nuclear hormone receptor binding
    		•  1.91348392022358 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.88834375049208 bayes_pls_golite062009
  • hormone receptor binding
    		•  1.8288193687002 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
    		•  1.49515149729803 bayes_pls_golite062009
  • transcription factor binding
    		•  1.38523780690867 bayes_pls_golite062009
  • steroid hormone receptor activity
    		•  1.28090460550476 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.26452462867497 bayes_pls_golite062009
  • transporter activity
    		•  0.768214707487563 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.644659911825478 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.61572149323953 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.58115018700114 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.50876329665586 bayes_pls_golite062009
  • structural molecule activity
    		•  0.441960874303873 bayes_pls_golite062009
  • receptor activity
    		•  0.230063209127305 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.187612502757984 bayes_pls_golite062009
  • catalytic activity
    		•  0.101795606736461 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle