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Protein Overview: its8

General Information:
Name(s) found: its8 / SPBC839.08c [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • pig-N [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 935 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [IDALink to PubMed article]
    fungal-type vacuole membrane [IDALink to PubMed article]
    integral to membrane [IEA]
    Golgi apparatus [IDALink to PubMed article]
    Biological Process: fungal-type cell wall organization [IGILink to PubMed article]
    GPI anchor biosynthetic process [IMPLink to PubMed article]
    Molecular Function: mannose-ethanolamine phosphotransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGRLLLLGI LFHVVFLKSI FDIYFVTPLI HGMKQYSAGE APAKRLFLIV GDGLRPDKLL  60
   61 QPHSEKVIGE EQTYAAPFLR SIIQNNGTFG VSHTRVPTES RPGHVALIAG FYEDVSAVTK 120
  121 GWKKNPVNFD SVFNQSRHTY SFGSEDILPM FSEGASDPSR VDTFMYSSEL EDFSSNGIVL 180
  181 DEWVFDRLDE LLAQSLEDKE LWDMLHRDKI VFFLHLLGID TIGHNKHPDS VEYVENIQYI 240
  241 DGKIQELVDK MNNYYNNDGA SSWVFTADHG MSDFGSHGDG NLDNTRTPII AWGAGIQSPT 300
  301 HEKNYGHDEY SLPWNLTEIK RIDIQQADIA ALMSYLVGLN FPVNSVGQIP LDYLDCSSRR 360
  361 KAEVALMNAL EIGEQYNLKS ASKDQTSIFF RPYSPLRNYT EVQASFYNSV IADIESGEYE 420
  421 IAIEHCFHFS QTVLSGLRYL QRYDWLLLRS IVFFGYLSWI GYVICFVFSL NIEPSSKIVK 480
  481 PVSVVKRVAF NIPFLLICIF FYIQSSPPFY YGYALFPTIF LQLIHSIFPN TKLGFKNFLT 540
  541 VAKQKHGFSL LKILFISLCI LCLLQFIVYS YFHREGFSVI LMGLAAWPWL LHADYAFSHK 600
  601 TISVSWSVLT SLLCFFTILP VNKKESLLFI FAGGFAMSVA GVFYILYRRN QAFQYSSTVT 660
  661 NKQLVLQVLI IMATVPVTLK IADSLQRNIA IPPILRLVAF GLFITSYIIP SHHIRSCKHY 720
  721 FLDRLAILFL TFSPTMCMLS ISFEALFYVV LFITLGLWME LETELQKYTE QLHPEYSRKK 780
  781 DAKFHLSLSH IRISLFFYIF INVAFFGTGN VASLSTFALD SVKRFIPVFN PVTQGALLMY 840
  841 TILVPFIALS AAFGIMNKRL GGIQQVTFFL AVGMADIVTI NFFYLVKDEG SWKDIGVSIS 900
  901 HFCISNFLIL FITALEHASA ILCKNITYTI HEKVN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..416] PSI-BLAST 41.0 Arylsulfatase A
    2 View Details [417..481] deduced N/A No confident structure predictions are available.
    3 View Details [482..638] deduced N/A No confident structure predictions are available.
    4 View Details [639..785] deduced N/A No confident structure predictions are available.
    5 View Details [786..935] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  3.93573675436765 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.50752017262291 bayes_pls_golite062009
  • catalytic activity
    		•  2.31328968099128 bayes_pls_golite062009
  • sulfuric ester hydrolase activity
    		•  2.02024402809818 bayes_pls_golite062009
  • phosphatase activity
    		•  1.06063475304592 bayes_pls_golite062009
  • binding
    		•  0.988674249789348 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.861123866751778 bayes_pls_golite062009
  • arylsulfatase activity
    		•  0.668750969117077 bayes_pls_golite062009
  • protein binding
    		•  0.392789852918493 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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