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Protein Overview: rga9

General Information:
Name(s) found: rga9 / SPAC1952.16 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • RhoGAp, GTPase activator towards Rho/Rac/Cdc42-like small GTPases [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 684 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: small GTPase mediated signal transduction [ISS]
    regulation of catalytic activity [IC]
    Molecular Function: GTPase activator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWDGFSNSFW SRDYITGINR AQRLINEGVE QNEKLLQLLH IRAKSASSCS DLLFKSFSKF  60
   61 NKHHPLNEES NDLPSDAAIH QLYESYLMEA SLHKKLGEQL NILVINPFAN WSKKYSRRVD 120
  121 EIVSAAIVKI NNYNSRFSHV NSKKSNLTDR KPIPTSRKSN KSDSLASALS QLDINPSNVN 180
  181 KFDGLINIVD HPYTAEEFAN VLLKLMKAST VKRKSYSHLG DYELVTNCSL LFEAIKTTFG 240
  241 LEKDSYVVKA GNQLIQHGLI RLLGIRRVFE NDPEIDAQFT TKSQQLLKSY HLSILEVDPY 300
  301 FQVNDPITAT NDDPVLQKYN LAYDNLEQCR HELELYLVLS IILLSFANPF QFMVFKDLEQ 360
  361 AELDRLNAVK SVLVECSNYS GNFIPSLNSI FIDNLNSFKN LDSLRDMSTQ INKHYTGYFI 420
  421 PVSNNELSTK DEYLFLQKSS LTEDNLIVSL VPKILAYLLD AYSYERDEEV LSCVWTTEVP 480
  481 LKDAFDLKSV LRKTDNVESV LNACVEKYTL SSITCSLRLC LLEFPDSLIR SSFYDYFKAI 540
  541 YTTYTDFEDL DHRLYSIKKC LLHLHSTPLH ILEEIIRHLS AYAISIRMKD GQIRHLAKII 600
  601 SPCVLRPPDD LNIIPVEDTH PTLLVIDLIN EFENLFADLE RPSTPPVEIE RALTPITTSP 660
  661 QKLKLPRSSS PCKNPSPTRR FRPF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..256] PSI-BLAST 27.69897 No description for 2eflA was found.
    2 View Details [257..684] PSI-BLAST 51.0 Crystal Structure of the Human Beta2-Chimaerin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  3.124619761789 bayes_pls_golite062009
  • binding
    		•  2.22529267810903 bayes_pls_golite062009
  • protein binding
    		•  1.87308005875135 bayes_pls_golite062009
  • identical protein binding
    		•  0.909409198394921 bayes_pls_golite062009
  • enzyme binding
    		•  0.58709209959999 bayes_pls_golite062009
  • GTPase binding
    		•  0.50066793947946 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.459881864914566 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.456472132383968 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.180886944097381 bayes_pls_golite062009
  • small GTPase binding
    		•  0.0531578648468707 bayes_pls_golite062009
    2
    Term Confidence Notes
  • Rho GTPase activator activity
    		•  4.58620967349979 bayes_pls_golite062009
  • Rac GTPase activator activity
    		•  4.48279904625182 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.68681762274025 bayes_pls_golite062009
  • actin binding
    		•  3.68337819140185 bayes_pls_golite062009
  • GTPase regulator activity
    		•  2.70614727793157 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  2.68579854252375 bayes_pls_golite062009
  • actin filament binding
    		•  2.37781909937968 bayes_pls_golite062009
  • microfilament motor activity
    		•  2.15518436158221 bayes_pls_golite062009
  • binding
    		•  2.15139804299723 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  2.06038764955701 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.9750017471254 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.95738547986197 bayes_pls_golite062009
  • diacylglycerol binding
    		•  1.32295764006263 bayes_pls_golite062009
  • protein binding
    		•  1.29100556128076 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  1.09070479183477 bayes_pls_golite062009
  • Rho guanyl-nucleotide exchange factor activity
    		•  0.967362611034944 bayes_pls_golite062009
  • Ras guanyl-nucleotide exchange factor activity
    		•  0.958295643211986 bayes_pls_golite062009
  • myosin heavy chain kinase activity
    		•  0.847021935833721 bayes_pls_golite062009
  • GTPase activator activity
    		•  0.717730683557543 bayes_pls_golite062009
  • enzyme activator activity
    		•  0.298334474872045 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0455432286632499 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle