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Protein Overview: rav1

General Information:
Name(s) found: rav1 / SPBC1105.10 [Sanger Pombe]
Description(s) found:
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  • pir||T39287 hypothetical protein SPBC1105.10 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74626365|sp|Q9Y817.1|RAV1_SCHPO RecName: Full=Putative regulator of V-ATPase in vacuolar membrane protein 1 [NCBI NR]
  • gi|5531472|emb|CAB50973.1| RAVE complex subunit Rav1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113258|ref|NP_596466.1| RAVE complex subunit Rav1 (predicted) [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • RAVE complex subunit Rav1 [Sanger Pombe]
  • Putative regulator of V-ATPase in vacuolar membrane protein 1 OS=Schizosaccharomyces pombe GN=rav1 PE=2 SV=1 [Swiss-Prot]
  • POSSIBLY INVOLVED IN REGULATION OF (H+)-ATPASE IN VACUOLAR MEMBRANE; SIMILAR TO S. CEREVISIAE RAV1: Q9Y817; [pompepVF.fasta]
  • PUTATIVE PROTEIN INVOLVED IN REGULATION OF (H+)-ATPASE IN VACUOLAR MEMBRANE; BY SIMILARITY TO YEAST RAV1: Q9Y817; [pompepV13]
  • Hypothetical protein [pompep4896]
  • |||possibly involved in regulation of (H+)-ATPase in vacuolar membrane [pompepnew.fasta]
  • SPBC1105.10 protein [4896.FASTAC]
  • |||involved in regulation of (H+)-ATPase in vacuolar membrane (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • hypothetical protein [Schizosaccharomyces pombe]gi|5531472|emb|CAB50973.1| SPBC1105.10 [Schizosaccharomyces pombe]gi|7491316|pir||T39287 hypothetical protein SPBC1105.10 - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||WD repeat protein |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (Q9Y817) Hypothetical protein [pompep4896_normal_reversed]
  • |rav1||RAVE complex subunit Rav1 |Schizosaccharomyces pombe|chr 2|||Manual [pombe030305.revfasta]
  • |rav1||RAVE complex subunit Rav1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC1105.10 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC1105.10 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Regulator of V-ATPase in vacuolar membrane protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rav1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 1297 amino acids

    Gene Ontology:
    Cellular Component: RAVE complex [IPILink to PubMed article]
    nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    endosome membrane [IDALink to PubMed article]
    Biological Process: regulation of proton-transporting ATPase activity, rotational mechanism [TASLink to PubMed article]
    vacuolar proton-transporting V-type ATPase complex assembly [TASLink to PubMed article]
    response to zinc ion [IMPLink to PubMed article]
    response to calcium ion [IMPLink to PubMed article]
    response to drug [IMPLink to PubMed article]
    late endosome to vacuole transport [TASLink to PubMed article]
    vacuolar acidification [IMPLink to PubMed article]
    Molecular Function: protein complex binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLAFTNPGT PLKRTAAYDN VQWNQNRILT FGTRYTVLII VNNYESYQNI QFGESIGAVA  60
   61 LDQRTGFLAI AHGQVLDIYK PADSLKWTHH YNYITQLSED ITQLSWGYNF DLLLCASSYT 120
  121 KLINFSEDKP RLVWSQNRIS DSFLSSTISS DACFIASIET KNPLAKVWQR TSPQGTVSSC 180
  181 DDFSYLVHPC RVRFSQWSKH LHPDASGSTP FLSTVGYDNV LRIWQVGSRF GSQLMHLSCF 240
  241 LNLRKYYKSD QPPYCCFIDK DDFTIALAHA ISRHSGQVHK DRILNRLLAL ASGQPHIFLL 300
  301 FTFECLYIFS LVIDQETLSS FELINQVPTN FPKGALQPDG FIPIYRTSKH EFYDYNIILF 360
  361 FQNSAREYMF SLTDFFYSDF ELRVSYDFYG HDYPIKSLTR TSNGHGIVSR DVNRICMFQS 420
  421 YISQDGKNQL ICRFRLLLGE SDFILPLYAG EYAAVLNLNS LKLWHCNEAI PPTLLCTCRQ 480
  481 VPTSPIITFF ILPVQNNDNS ALCALTEGGH AWFWSVSNEA HDGSAVLRFI DRVNFTKNLN 540
  541 IASAVDVMGW SSTLNLSSLS SFDQEVFQSI SKDGLLQTWM ARVLGDDKAE ISEISKVQTS 600
  601 IKSATMIKGS TSKKVAVVSE NNRRLSIFDT RSSEFSEKEE FSSVFDDYGP INDLDWTSTP 660
  661 NSHSILAVGF LHDVILLCQN RRSYMNDIPC WSRIRRYNLL EYTNSLISDS SWLDNGTLVT 720
  721 AIGNGLFYFD NSLPEDQSLL FPASLKRSAK NIFDLAYQLN GILPVFHPQL LQQLLLRNQP 780
  781 FLFTNILLRF YLCLKDDVDM HFLLNMDCSE FYCCDEEISK DLLIKSLSQN SAEILNPAEL 840
  841 DFEETSVSKH LGLYIDEMIK KLTALLKVKK VKTLTRSSQF LLLNLIEAFN KARALRDSLD 900
  901 LNGKRYCIML NQYVLSKHQR QLTSLPTREM AWAFHSSNKA VLLDHTKKLH GKPLLWNAVE 960
  961 EYAIPFWLNE QLLKDVFLEL SRNHYAEIDD RNPENVSLYH IALHKINVFR DLWRLASWHK1020
 1021 ESARTVKLLS NDFSKKKWKV VASKNAFALL SKHRYFYASA FFLLADSCYD AAKVCIRNLK1080
 1081 SISLAIAMTR VYEGDDGPTL KRLINEYVLP LAVSQNDRWL TNWSFTILKQ EKKALQSLVS1140
 1141 PIRSLVSDND FIQLYTSDKN DQEIHENKDS QRNSTNEPVR NKFPSDDPAF ILLYECLRSS1200
 1201 NVQIDESLEY RFVLHNANVY CQLGCDLIAL GLLRNWKFQK NPATAHLETE DYMVTDKQSA1260
 1261 VEKTHDSPKL GKTLMGQDIR PTPDDVPEFN ESAFSFE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..732] PSI-BLAST 27.522879 Actin interacting protein 1
    2 View Details [733..951] deduced N/A No confident structure predictions are available.
    3 View Details [952..1223] MSA 1.048941 View MSA. No confident structure predictions are available.
    4 View Details [1224..1297] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • protein binding
    		•  1.21879977456466 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.579815310385678 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.570141050045461 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.479978536094414 bayes_pls_golite062009
    		• 0.45054027253231 bayes_pls_golite062009
  • DNA binding
    		•  0.0736878329528894 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.77

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle