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View Structure Prediction Details

Protein: rav1
Organism: Schizosaccharomyces pombe
Length: 1297 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rav1.

Description E-value Query
Range
Subject
Range
gi|40746323, gi|... - gi|67516843|ref|XP_658307.1| hypothetical protein AN0703.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
919.0 [0..2] [1262..50]
gi|169763226 - gi|169763226|ref|XP_001727513.1| hypothetical protein [Aspergillus oryzae RIB40]
gi|83770541 - gi|83770541|dbj|BAE60674.1| unnamed protein product [Aspergillus oryzae]
885.0 [0..3] [1246..1]
RAV1 - Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzym...
RAV1_YEAST - Regulator of V-ATPase in vacuolar membrane protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508...
884.0 [0..7] [1282..6]
gi|46138411, gi|... - gi|46138411|ref|XP_390896.1| hypothetical protein FG10720.1 [Gibberella zeae PH-1], gi|42552134|gb|E...
866.0 [0..3] [1250..1138]
gi|159131494 - gi|159131494|gb|EDP56607.1| WD repeat protein [Aspergillus fumigatus A1163]
gi|70995968, gi|... - gi|70995968|ref|XP_752739.1| WD repeat protein [Aspergillus fumigatus Af293], gi|66850374|gb|EAL9070...
864.0 [0..3] [1233..1]
gi|20145245 - gi|20145245|emb|CAD29602.1| hypothetical protein, conserved [Aspergillus fumigatus]
863.0 [0..3] [1233..1]
gi|16944675 - gi|16944675|emb|CAB99185.2| conserved hypothetical protein [Neurospora crassa]
854.0 [0..22] [1266..35]
gi|85079043 - gi|85079043|ref|XP_956280.1| hypothetical protein [Neurospora crassa OR74A]
gi|32415235, gi|... - gi|32415235|ref|XP_328097.1| hypothetical protein [Neurospora crassa], gi|28917336|gb|EAA27044.1| hy...
853.0 [0..28] [1266..2]
gi|115492071, gi... - gi|115492071|ref|XP_001210663.1| conserved hypothetical protein [Aspergillus terreus NIH2624], gi|11...
809.0 [0..83] [1262..2]
gi|90302741, gi|... - gi|90302741|gb|EAS32372.1| hypothetical protein CIMG_03396 [Coccidioides immitis RS], gi|119186697|r...
803.0 [0..3] [1275..1]

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Predicted Domain #1
Region A:
Residues: [1-732]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLAFTNPGT PLKRTAAYDN VQWNQNRILT FGTRYTVLII VNNYESYQNI QFGESIGAVA  60
   61 LDQRTGFLAI AHGQVLDIYK PADSLKWTHH YNYITQLSED ITQLSWGYNF DLLLCASSYT 120
  121 KLINFSEDKP RLVWSQNRIS DSFLSSTISS DACFIASIET KNPLAKVWQR TSPQGTVSSC 180
  181 DDFSYLVHPC RVRFSQWSKH LHPDASGSTP FLSTVGYDNV LRIWQVGSRF GSQLMHLSCF 240
  241 LNLRKYYKSD QPPYCCFIDK DDFTIALAHA ISRHSGQVHK DRILNRLLAL ASGQPHIFLL 300
  301 FTFECLYIFS LVIDQETLSS FELINQVPTN FPKGALQPDG FIPIYRTSKH EFYDYNIILF 360
  361 FQNSAREYMF SLTDFFYSDF ELRVSYDFYG HDYPIKSLTR TSNGHGIVSR DVNRICMFQS 420
  421 YISQDGKNQL ICRFRLLLGE SDFILPLYAG EYAAVLNLNS LKLWHCNEAI PPTLLCTCRQ 480
  481 VPTSPIITFF ILPVQNNDNS ALCALTEGGH AWFWSVSNEA HDGSAVLRFI DRVNFTKNLN 540
  541 IASAVDVMGW SSTLNLSSLS SFDQEVFQSI SKDGLLQTWM ARVLGDDKAE ISEISKVQTS 600
  601 IKSATMIKGS TSKKVAVVSE NNRRLSIFDT RSSEFSEKEE FSSVFDDYGP INDLDWTSTP 660
  661 NSHSILAVGF LHDVILLCQN RRSYMNDIPC WSRIRRYNLL EYTNSLISDS SWLDNGTLVT 720
  721 AIGNGLFYFD NS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.522879
Match: 1pguA
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.42570478946173 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
transcription regulator activity 0.579815310385678 bayes_pls_golite062009
nucleic acid binding 0.570141050045461 bayes_pls_golite062009
substrate-specific transporter activity 0.479978536094414 bayes_pls_golite062009
0.45054027253231 bayes_pls_golite062009
DNA binding 0.0736878329528894 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [733-951]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPEDQSLLFP ASLKRSAKNI FDLAYQLNGI LPVFHPQLLQ QLLLRNQPFL FTNILLRFYL  60
   61 CLKDDVDMHF LLNMDCSEFY CCDEEISKDL LIKSLSQNSA EILNPAELDF EETSVSKHLG 120
  121 LYIDEMIKKL TALLKVKKVK TLTRSSQFLL LNLIEAFNKA RALRDSLDLN GKRYCIMLNQ 180
  181 YVLSKHQRQL TSLPTREMAW AFHSSNKAVL LDHTKKLHG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [952-1223]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPLLWNAVEE YAIPFWLNEQ LLKDVFLELS RNHYAEIDDR NPENVSLYHI ALHKINVFRD  60
   61 LWRLASWHKE SARTVKLLSN DFSKKKWKVV ASKNAFALLS KHRYFYASAF FLLADSCYDA 120
  121 AKVCIRNLKS ISLAIAMTRV YEGDDGPTLK RLINEYVLPL AVSQNDRWLT NWSFTILKQE 180
  181 KKALQSLVSP IRSLVSDNDF IQLYTSDKND QEIHENKDSQ RNSTNEPVRN KFPSDDPAFI 240
  241 LLYECLRSSN VQIDESLEYR FVLHNANVYC QL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [1224-1297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GCDLIALGLL RNWKFQKNPA TAHLETEDYM VTDKQSAVEK THDSPKLGKT LMGQDIRPTP  60
   61 DDVPEFNESA FSFE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle