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Protein Overview: klp8

General Information:
Name(s) found: klp8 / SPAC144.14 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • kinesin-like protein Klp8 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 511 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cell division site [IDALink to PubMed article]
    cell tip [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    medial cortical node [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    Biological Process: microtubule-based movement [IEA]
    Molecular Function: ATP binding [IEA]
    microtubule motor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTANVRVIV RVRPKSLREL SKSAEDLLSV DSHNKTVTIT PPKHGLKHSR HKNRVNGPRT  60
   61 FAFDECFAPS APESKNLSGQ EDVYESTGPL LVKSILEGFN SCFITYGQKG TGKTYSVVGL 120
  121 RGQPGIIPHI SESIFEEIDK LKKKSPNTTI TVSISLAEII EETPYDLLQP NVNSSHTPGE 180
  181 TVFVQKDSLT GYHLHGLSEF EVGSAQEIDA FLRLAAKNIR TELSDISGVR KGHSVFSLVV 240
  241 QQRIIDPKTR HSLKKASRLQ IIDLASFSKG SQRNESISSF ESSSNNKSLS VLNRVIAALT 300
  301 SKKNDVLIPY KDSVLTTLLQ DALGGNCRTI MLTCVSPCDF DDTFSALRYS EAARRIKNIS 360
  361 NINCKEAYST NNEGELDDIL TTLESDREQL RRHEEHSQKL LKFIEEIRND YEERIHALES 420
  421 QNSALKAHLR LAVDAYLNPL EFNFDDKNVK LKEFGSPNIA YKQELNSFQG ELSSLFKDLK 480
  481 LVKSQLHDYP KPEVSDIDMD MESLRHDSLL D

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..363] PSI-BLAST 86.0 Kinesin
    2 View Details [364..511] PSI-BLAST 11.522879 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • microtubule motor activity
    		•  7.68336791348661 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  4.97507344344589 bayes_pls_golite062009
  • motor activity
    		•  4.04927796049806 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.69246499202248 bayes_pls_golite062009
  • tubulin binding
    		•  2.67743463093593 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.61582393123755 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.59641929642359 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.59333672868803 bayes_pls_golite062009
  • microtubule binding
    		•  2.59155206524122 bayes_pls_golite062009
  • binding
    		•  2.4974940028864 bayes_pls_golite062009
  • transporter activity
    		•  2.17383908004663 bayes_pls_golite062009
  • ATPase activity
    		•  2.11122403732968 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.02444700826552 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.8908019270286 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.50574672650697 bayes_pls_golite062009
  • hydrolase activity
    		•  1.35268825531078 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.97700154207756 bayes_pls_golite062009
  • actin binding
    		•  0.875514430441177 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.725611289205392 bayes_pls_golite062009
  • nucleotide binding
    		•  0.717697610309727 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.713814218071151 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.713752628021599 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.608058786636536 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.2911562221251 bayes_pls_golite062009
  • protein binding
    		•  0.193768631623192 bayes_pls_golite062009
  • ATP binding
    		•  0.19169045543599 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.165732470448462 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.162060759063149 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.114463153989353 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.081265446432119 bayes_pls_golite062009
  • DNA binding
    		•  0.0759947537748353 bayes_pls_golite062009
  • minus-end-directed microtubule motor activity
    		•  0.068779631341469 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle