Protein Overview: apc2

General Information:
Name(s) found:	apc2 / SPBP23A10.04 [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	gi\|74620124\|sp\|Q874R3.1\|APC2_SCHPO RecName: Full=Anaphase-promoting complex subunit 2; AltName: Full=20S cyclosome/APC complex protein apc2 [NCBI NR] gi\|68011924\|ref\|NP_001018806.1\| anaphase-promoting complex subunit Apc2 (PMID 12477395) [Schizosaccharomyces pombe] [NCBI NR] gi\|28207841\|emb\|CAD62574.1\| anaphase-promoting complex subunit Apc2 [Schizosaccharomyces pombe] [NCBI NR] anaphase-promoting complex subunit Apc2 [Sanger Pombe] Anaphase-promoting complex subunit 2 OS=Schizosaccharomyces pombe GN=apc2 PE=1 SV=1 [Swiss-Prot] Anaphase-promoting complex (APC ) (PMID 12477395), required for cyclin degradation, possibly required for metaphase-anaphase transition, cullin family, similar to S. cerevisiae APC2 [pompep4896] \|apc2\|\|anaphase-promoting complex (APC) (PMID 12477395) [pompepnew.fasta] Apc2 protein (Spbp23a10.04 protein) [4896.FASTAC] \|apc2\|\|anaphase-promoting complex (APC) (PMID 12477395)\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pombe041504.fasta] apc2 [Schizosaccharomyces pombe] [nrdb_11152004_Chlamydomonas] \|apc2\|\|anaphase-promoting complex \|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pompep2242005.fasta] (Q874R3) Anaphase-promoting complex (APC ) (PMID 12477395), required for cyclin degradation, possibly required for metaphase-anaphase transition, cullin family, similar to S. cerevisiae APC2 [pompep4896_normal_reversed] \|apc2\|\|anaphase-promoting complex subunit Apc2\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] Anaphase-promoting complex subunit 2 (20S cyclosome/APC complex protein apc2) [nr-271106-contam.fasta] hypothetical protein SPBP23A10.04 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] SPBP23A10.04 [Schizosaccharomyces pombe] [nr-271106-contam.fasta] \|apc2\|\|anaphase-promoting complex cullin family subunit Apc2\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [Other_S_Pombe_12-15-2011_reversed.fasta] Anaphase-promoting complex subunit 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=apc2 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	681 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cullin-RING ubiquitin ligase complex [IEA] anaphase-promoting complex [IDA] cytosol [IDA]
Biological Process:	cyclin catabolic process [IC] anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [IC] mitotic metaphase/anaphase transition [IC] protein ubiquitination [IC]
Molecular Function:	ubiquitin-protein ligase activity [IC] protein binding [IPI] ubiquitin protein ligase binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDTDLSTFT GRSLLIDQLS SVTQGTPVLD FIDKLRIHFY TTIRQNLLKI DLKNICSLHD  60
   61 LTDQLSDFWL VYEQSVLESP ILSPELDRIL TCFRCLCRRY LPISVIESVL TEYLDQVLKV 120
  121 WLESKTNPCL DMEKFFQLCE KFKQLGLSSV LKERFVYVLQ LHVGSLLTTR YAMSWEQSVY 180
  181 HEALEWIRTE FGVLVEHVFS LSNPAVLVQL DHLVSQILAH LRSDNILDIV LHYPNSLGAI 240
  241 EDLRLVARQK QQRQYLTETF VKDCTSSILT ASSDSSYILL FYVSTIRCFV ALDPPGVLLD 300
  301 KAAKPIRSFL NEREDAYKCL VSLLFVDGEK GLRSELSQIP TENIDSTTDR FDNYHWMPDP 360
  361 IDAAPDFKKP TDRDVVGSLI SIFKSKEPLV KELQLLLADR LLQLTDYHYE VEAKNIEFLK 420
  421 YRFGETVLQM CSVMLNDIEN SRFIDQSIHM ENYVSKGLHV TILSRLFWPT LSVRYFHLPG 480
  481 PLKKELDAYA EEYRERKRKR ELVFLPNLGS VELEIELEDR TLTLTVTPEQ AAFISLFEET 540
  541 STLHIEKAAE LLDQPKEIVE RHLKFWLHHR VLTDIGDDRY RVRETEAETA TETVLDEIQG 600
  601 VSAVQSEAES SAAEMRVYWS FVVGMLTNLG ALELERIHNM LTMFIPPPNG YTRTQSELRE 660
  661 FLALMIKEEK LEFTGGAYKL K

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	None Entered	Lid1-TAP APC complex on iontrap.	Unpublished Data

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.89

Protein Overview: apc2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: