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Protein Overview: SPBC2G5.05

General Information:
Name(s) found: SPBC2G5.05 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • transketolase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 685 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: pentose-phosphate shunt, non-oxidative branch [ICLink to PubMed article]
    Molecular Function: transketolase activity [ISSLink to PubMed article]
    calcium ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSSSYTDID TLAINTIRTL AVDTTAHAKS GHPGAPMGLA PAAHVLFSRI MKFNPAHPKW  60
   61 LNRDRFILSN GHACVLQYIM CHLLGYKLTI EDLKQFRQVG SKTPGHPETH NPDLNIETGA 120
  121 GPLGQGIASA VGLAIGKAHS AAVYNKPGFD LFSNYTFCFL GDGCLQEGVS SEACSLAGHL 180
  181 KLSNLIAVWD NNKITIDGAT SMSFDEDVEK RFEAYGWNIV RVANGDTDLD GIEKGFREAM 240
  241 SCTDKPTLIN LKTTIGYGSE LQGTHSVHGS PLKPEDCVHV KKLFGFDPTK TFQVPPEVYA 300
  301 YYKERVAIAS SAEEEYKKMY ASYKQSYPDL SNQLERILSR KFPEGWEKHL PVYKPGDKAV 360
  361 ATRKLSEIVL DALCPVLPEL VGGSADLTPS NLTRWEGAAD FQPPSSKLGT YAGRYIRYGI 420
  421 REHGMAGIMN GLAVYGPIIP YGGTFLNFVS YAAGAVRMAA LNNSRVIYVA THDSIGLGED 480
  481 GPTHQPIETF AHFRAMPNIN CWRPADGNET SAAYYSALTS DSTPSILALT RQNLPQLENS 540
  541 TIENALKGGY VMLENKEADI TLVGTGSEVS LCIDTVKTLE TEYNLKARVV SLPCWEVFEQ 600
  601 QPESYRLSVI PDGIPAMSVE VWATNGWRRY VHEAFGMHTF GDSGPAPKLY EKFHFTTSGV 660
  661 AQRAKKTVDA YKDIPYIRSP VRRAF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..685] PSI-BLAST 178.0 Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transketolase activity
    		•  6.17852985073866 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  2.93250853993668 bayes_pls_golite062009
  • pyruvate dehydrogenase activity
    		•  2.81702263447118 bayes_pls_golite062009
  • pyruvate dehydrogenase (acetyl-transferring) activity
    		•  2.6977837113283 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  2.21959520697519 bayes_pls_golite062009
  • binding
    		•  0.980920092099572 bayes_pls_golite062009
  • catalytic activity
    		•  0.545407789079971 bayes_pls_golite062009
  • thiamin pyrophosphate binding
    		•  0.297191393111081 bayes_pls_golite062009
  • acetolactate synthase activity
    		•  0.173822256668691 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.76

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle