YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC2G5.05
Organism:	Schizosaccharomyces pombe
Length:	685 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC2G5.05.

Description	E-value	Query Range	Subject Range
gi\|11595598 - gi\|11595598\|emb\|CAC18218.1\| probable TRANSKETOLASE [Neurospora crassa] gi\|157071283, gi... - gi\|164426308\|ref\|XP_961414.2\| transketolase [Neurospora crassa OR74A], gi\|157071283\|gb\|EAA32178.2\| t...	647.0	[0..5]	[685..3]
gi\|85102892 - gi\|85102892\|ref\|XP_961414.1\| hypothetical protein ( (AL451017) probable TRANSKETOLASE [Neurospora cr... gi\|32412682, gi\|... - gi\|32412682\|ref\|XP_326821.1\| hypothetical protein ( (AL451017) probable TRANSKETOLASE [Neurospora cr...	642.0	[0..5]	[685..3]
gi\|145013920, gi... - gi\|39968757\|ref\|XP_365769.1\| conserved hypothetical protein [Magnaporthe grisea 70-15], gb\|EAA54486....	634.0	[0..4]	[685..1]
gi\|90298766, gi\|... - gi\|90298766\|gb\|EAS28397.1\| hypothetical protein CIMG_09601 [Coccidioides immitis RS], gi\|119175544\|r...	632.0	[0..4]	[685..1]
gi\|42546500, gi\|... - gi\|46136965\|ref\|XP_390174.1\| hypothetical protein FG09998.1 [Gibberella zeae PH-1], gi\|42546500\|gb\|E...	628.0	[0..8]	[685..5]
gi\|115492021, gi... - gi\|115492021\|ref\|XP_001210638.1\| transketolase 1 [Aspergillus terreus NIH2624], gi\|114197498\|gb\|EAU3...	627.0	[0..4]	[685..1]
gi\|70995930, gi\|... - gi\|70995930\|ref\|XP_752720.1\| transketolase TktA [Aspergillus fumigatus Af293], gi\|66850355\|gb\|EAL906... gi\|159131475 - gi\|159131475\|gb\|EDP56588.1\| transketolase TktA [Aspergillus fumigatus A1163]	626.0	[0..4]	[685..1]
gi\|88183248, gi\|... - gi\|88183248\|gb\|EAQ90716.1\| conserved hypothetical protein [Chaetomium globosum CBS 148.51], gi\|11620...	624.0	[0..18]	[685..9]
gi\|83770558 - gi\|83770558\|dbj\|BAE60691.1\| unnamed protein product [Aspergillus oryzae] gi\|169763260 - gi\|169763260\|ref\|XP_001727530.1\| hypothetical protein [Aspergillus oryzae RIB40]	622.0	[0..4]	[685..1]
gi\|49085400, gi\|... - gi\|67516813\|ref\|XP_658292.1\| hypothetical protein AN0688.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	620.0	[0..4]	[685..1]

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Predicted Domain #1

Region A:
Residues: [1-685]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSSSYTDID TLAINTIRTL AVDTTAHAKS GHPGAPMGLA PAAHVLFSRI MKFNPAHPKW  60
   61 LNRDRFILSN GHACVLQYIM CHLLGYKLTI EDLKQFRQVG SKTPGHPETH NPDLNIETGA 120
  121 GPLGQGIASA VGLAIGKAHS AAVYNKPGFD LFSNYTFCFL GDGCLQEGVS SEACSLAGHL 180
  181 KLSNLIAVWD NNKITIDGAT SMSFDEDVEK RFEAYGWNIV RVANGDTDLD GIEKGFREAM 240
  241 SCTDKPTLIN LKTTIGYGSE LQGTHSVHGS PLKPEDCVHV KKLFGFDPTK TFQVPPEVYA 300
  301 YYKERVAIAS SAEEEYKKMY ASYKQSYPDL SNQLERILSR KFPEGWEKHL PVYKPGDKAV 360
  361 ATRKLSEIVL DALCPVLPEL VGGSADLTPS NLTRWEGAAD FQPPSSKLGT YAGRYIRYGI 420
  421 REHGMAGIMN GLAVYGPIIP YGGTFLNFVS YAAGAVRMAA LNNSRVIYVA THDSIGLGED 480
  481 GPTHQPIETF AHFRAMPNIN CWRPADGNET SAAYYSALTS DSTPSILALT RQNLPQLENS 540
  541 TIENALKGGY VMLENKEADI TLVGTGSEVS LCIDTVKTLE TEYNLKARVV SLPCWEVFEQ 600
  601 QPESYRLSVI PDGIPAMSVE VWATNGWRRY VHEAFGMHTF GDSGPAPKLY EKFHFTTSGV 660
  661 AQRAKKTVDA YKDIPYIRSP VRRAF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	178.0
Match:	1tkaA
Description:	Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transketolase activity	6.17852985073866	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	2.93250853993668	bayes_pls_golite062009
pyruvate dehydrogenase activity	2.81702263447118	bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity	2.6977837113283	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.21959520697519	bayes_pls_golite062009
binding	0.980920092099572	bayes_pls_golite062009
catalytic activity	0.545407789079971	bayes_pls_golite062009
thiamin pyrophosphate binding	0.297191393111081	bayes_pls_golite062009
acetolactate synthase activity	0.173822256668691	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: