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Protein Overview: pli1

General Information:
Name(s) found: pli1 / SPAC1687.05 [Sanger Pombe]
Description(s) found:
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  • pir||T37748 septin interacting protein homolog - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|59800142|sp|O94451.3|PLI1_SCHPO RecName: Full=E3 SUMO-protein ligase pli1 [NCBI NR]
  • gi|4106659|emb|CAA22599.1| SUMO E3 ligase Pli1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114035|ref|NP_593123.1| SUMO E3 ligase Pli1 [Schizosaccharomyces pombe] [NCBI NR]
  • SUMO E3 ligase Pli1 [Sanger Pombe]
  • E3 SUMO-protein ligase pli1 OS=Schizosaccharomyces pombe GN=pli1 PE=1 SV=3 [Swiss-Prot]
  • SEPTIN INTERACTING PROTEIN HOMOLOG: O94451; [pompepVF.fasta]
  • Hypothetical 80.7 kDa protein C1687.05 in chromosome I [pompep4896]
  • |reserved_name_pli1||septin interacting protein homolog [pompepnew.fasta]
  • |pli1||septin interacting protein homolog|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • |pli1||SUMO E3 ligase Pli1|Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • septin interacting protein homolog [Schizosaccharomyces pombe]gi|4106659|emb|CAA22599.1| SPAC1687.05 [Schizosaccharomyces pombe]gi|7493364|pir||T37748 septin interacting protein homolog - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • (O94451) Hypothetical 80.7 kDa protein C1687.05 in chromosome I [pompep4896_normal_reversed]
  • hypothetical protein SPAC1687.05 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • E3 SUMO--protein ligase pli1 [nr-271106-contam.fasta]
  • SPAC1687.05 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • E3 SUMO-protein ligase pli1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pli1 PE=1 SV=3 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 727 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: regulation of chromosome segregation [IMPLink to PubMed article]
    protein sumoylation [IMPLink to PubMed article]
    regulation of mitotic recombination [IMPLink to PubMed article]
    regulation of telomere maintenance [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    SUMO ligase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQANFLQEL PNVLKRLETG LIIPQLKDIL RVFGLRLSGT KAELITRIKQ LIERIAIENN  60
   61 TTSWEALKKA IDGDVTSAVC ILKYNTYQIY SAAAPIAPPS SASGNRSYSR PFAPVVHSRI 120
  121 RFRKSPFYDI LEQFNAPFVV PACVGTRNTI SFSFHVTPPA LSKLLNDPKQ YRVYLFSTPS 180
  181 ETIGFGNCLM EFPTPQMELR INNQVAHANY RRLKGKPGTT NPADITDLVS KYAGPPGNNV 240
  241 VIYYMNSTKS YSVVVCFVKV YTIENLVDQI KSRKAESKEK IIERIKNDNQ DADIIATSTD 300
  301 ISLKCPLSFS RISLPVRSVF CKHIQCFDAS AFLEMNKQTP SWMCPVCASH IQFSDLIIDG 360
  361 FMQHILESTP SNSETITVDP EGNWKLNTFD EPVESSEDEF VPKEKVIELS DGEGISTMAN 420
  421 KSNDQPTRRA STHNSGPPAK RKRESLVIDL TISDDDENVA TSTTESPSNA TKENSLSRNV 480
  481 QSPNIDTAIS NRSTNVRHGH PGFKDYTVEN SPASRERSTS ESAQSSVHMG YAGEGGLLSG 540
  541 ALRAPSQQNN NNSNTQHSIN LHTIVPSPYE PPLSVTPSTA ITNLSIPESN RTNSSASSKS 600
  601 FTMNDLILPP LHLKNTTQTN NAHEDAQSSN LSQNHSLFYE RIPQRPSYRI EKQNKGIYED 660
  661 ENEQSISAMP IPRAHPQLPK NLLSQTAGPL WDEQQDAQVD WNSELQSNNS YHNSGFEGTG 720
  721 NTFQSID

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..74] PSI-BLAST 16.39794 Solution structure of human p53 binding domain of PIAS-1
    2 View Details [75..261] deduced N/A No confident structure predictions are available.
    3 View Details [262..403] FFAS03 1.86 No description for 2cklB was found.
    4 View Details [404..727] FFAS03 1.31 THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • SUMO ligase activity
    		•  7.09211721404578 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  5.19208367271658 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.23914967265256 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.15902332919799 bayes_pls_golite062009
  • DNA binding
    		•  2.92139817158415 bayes_pls_golite062009
  • binding
    		•  2.85946414867169 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.76384947675043 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.74673402515898 bayes_pls_golite062009
  • transcription factor binding
    		•  1.8538346588987 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.68730216999933 bayes_pls_golite062009
  • protein binding
    		•  1.4634286530239 bayes_pls_golite062009
  • transcription activator activity
    		•  1.25644547219412 bayes_pls_golite062009
  • nuclear hormone receptor binding
    		•  1.20451045950565 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.16985510361731 bayes_pls_golite062009
  • steroid hormone receptor binding
    		•  1.14520328838371 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.08109201779928 bayes_pls_golite062009
  • androgen receptor binding
    		•  0.98494234316847 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.84593119507905 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.84537546395033 bayes_pls_golite062009
  • hormone receptor binding
    		•  0.81375575057479 bayes_pls_golite062009
  • catalytic activity
    		•  0.454272578060498 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.258128144495696 bayes_pls_golite062009
  • ligase activity
    		•  0.165914056383691 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.00901028599610032 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle