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Protein Overview: usp105

General Information:
Name(s) found: usp105 / SPBC4B4.09 [Sanger Pombe]
Description(s) found:
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  • pir||T40481 hypothetical protein SPBC4B4.09 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74626935|sp|O74970.1|PRP39_SCHPO RecName: Full=Pre-mRNA-processing factor 39 [NCBI NR]
  • gi|3169096|emb|CAA19289.1| U1 snRNP-associated protein Usp105 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113218|ref|NP_596426.1| U1 snRNP-associated protein Usp105 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • U1 snRNP-associated protein Usp105 [Sanger Pombe]
  • Pre-mRNA-processing factor 39 OS=Schizosaccharomyces pombe GN=prp39 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE PRE-MRNA SPLICING FACTOR; U1 SNRNA- ASSOCIATED PROTEIN; SIMILAR TO S. CEREVISIAE PRP39: O74970; [pompepVF.fasta]
  • PUTATIVE PRE-MRNA SPLICING FACTOR; U1 SNRNA-ASSOCIATED PROTEIN; SIMILAR TO S. CEREVISIAE PRP39: O74970; [pompepV13]
  • Possible pre-mRNA processing by similarity to yeast prp39 [pompep4896]
  • |prp39||putative pre-mRNA splicing factor [pompepnew.fasta]
  • SPBC4B4.09 protein (Prp39 protein) [4896.FASTAC]
  • |prp39||U1 snRNA-associated protein|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • possible pre-mRNA processing by similarity to yeast prp39 [Schizosaccharomyces pombe]gi|3169096|emb|CAA19289.1| SPBC4B4.09 [Schizosaccharomyces pombe]gi|7491683|pir||T40481 hypothetical protein SPBC4B4.09 - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • (O74970) Possible pre-mRNA processing by similarity to yeast prp39 [pompep4896_normal_reversed]
  • |usp105|prp39|U1 snRNP-associated protein Usp105|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC4B4.09 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Pre-mRNA-processing protein prp39 [nr-271106-contam.fasta]
  • hypothetical protein SPBC4B4.09 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Pre-mRNA-processing factor 39 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=prp39 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 612 amino acids

    Gene Ontology:
    Cellular Component: commitment complex [ISSLink to PubMed article]
    U1 snRNP [IDALink to PubMed article]
    Biological Process: nuclear mRNA 5'-splice site recognition [IC][ISSLink to PubMed article]
    nuclear mRNA splicing, via spliceosome [ISSLink to PubMed article]
    Molecular Function: pre-mRNA 5'-splice site binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYGDIYIAE ETEWDKYNRQ INKNPDDFDA WEGLVRASEH LEGGVGRNSS KQAINTLRSV  60
   61 YDRFLGKYPL LFGYWKKYAD FEFFVAGAEA SEHIYERGIA GIPHSVDLWT NYCAFKMETN 120
  121 GDANEVRELF MQGANMVGLD FLSHPFWDKY LEFEERQERP DNVFQLLERL IHIPLHQYAR 180
  181 YFERFVQVSQ SQPIQQLLPP DVLASIRADV TREPAKVVSA GSKQITVERG ELEIEREMRA 240
  241 RIYNIHLQIF QKVQLETAKR WTFESEIKRP YFHVKELDEA QLVNWRKYLD FEEVEGDFQR 300
  301 ICHLYERCLI TCALYDEFWF RYARWMSAQP DHLNDVSIIY ERASCIFASI SRPGIRVQYA 360
  361 LFEESQGNIA SAKAIYQSIL TQLPGNLEAV LGWVGLERRN APNYDLTNAH AVLRSIINEG 420
  421 KCNTGITEVL ITEDIKLVWK IEGDIELARN MFLQNAPALL DCRHFWISFL RFELEQPLNS 480
  481 KNYTEHHARV SNVMEMIRNK TRLPPRTIMD LTKLYMEYLC HQSNDPSVLQ EYLLIDRDVF 540
  541 GPFSVRESHW KKLDEGQDLK QVSTRLLSTN GHPGISVNEA KIKSGESPYE KYYRLQGVVE 600
  601 TVTSGVAANG SS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..539] PSI-BLAST 16.522879 No description for 2ooeA was found.
    2 View Details [540..612] PSI-BLAST 4.39794 Crystal Structure Analysis of ClpB

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  2.76684454218635 bayes_pls_golite062009
  • binding
    		•  2.57186536498101 bayes_pls_golite062009
  • protein binding
    		•  1.83529176977066 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.26149030245805 bayes_pls_golite062009
  • DNA binding
    		•  0.9531600253493 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.93037889019021 bayes_pls_golite062009
  • signal sequence binding
    		•  0.8574224889202 bayes_pls_golite062009
  • transcription factor activity
    		•  0.374364600772076 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle