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Protein Overview: SPAC23C4.03

General Information:
Name(s) found: SPAC23C4.03 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • haspin related kinase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 488 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: regulation of sister chromatid cohesion [ISS]
    protein amino acid phosphorylation [ICLink to PubMed article]
    regulation of mitotic cell cycle [ISS]
    Molecular Function: ATP binding [ISSLink to PubMed article]
    protein serine/threonine kinase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESRSKVKTY GKNRRYINKD IEIWASLDER PCALKPRNIE NFNNQERSDL EHIHSKPKKD  60
   61 SLLSWNILLK KGSYKENELL AKRNQNLVPT VIIPASPRDN ASKSVVSKKE VVNLSSSVAL 120
  121 SGKPANNSKL DPLHRLLQIV AQEDALPFSQ FVKSQTFEIQ KIGEASYSEV YQASNADDVP 180
  181 VVWKVIPFGE DGQAQYADVL NEVQISQWIK VDGFANLHQV VVVKGTYPSL LLEEWDRYLM 240
  241 QNGSENDRPD SYSSTQLYCV LCLDHSGTDL EHFELRSWRE CWSVFYETLK ILSLVETRYE 300
  301 FEHRDLHWGN ILIRKADRSE EEVSFLLNEI SLDDIESVDF PGSQDKADDF DNILQVTLID 360
  361 FTLARASYSQ GIISYNEFND PDLFNGVDDY QFDIYRLMSR VTKGRWAQFF PITNVLWLHY 420
  421 LIHQLLHKKN LSSPLTETET LMRSRLKQIF RLIDPVKTMQ FQQAEDSIRS KSTVTSATSL 480
  481 LNWVRQKY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] deduced N/A No confident structure predictions are available.
    2 View Details [128..488] PSI-BLAST 62.0 MAP kinase p38

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • transferase activity
    		•  3.97138602499442 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  1.3898059094397 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.38496328649031 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  1.27291233344322 bayes_pls_golite062009
  • protein binding
    		•  1.22565748038754 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.684204466593894 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.499492353295369 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.35402045013148 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.26024936404169 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  0.196560862858137 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle