Protein Overview: SPCC18.08

General Information:
Name(s) found:	SPCC18.08 [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	pir\|\|T41151 lysyl-trna synthetase - fission yeast (Schizosaccharomyces pombe) [NCBI NR] gi\|74582575\|sp\|O74858.1\|SYKM_SCHPO RecName: Full=Lysyl-tRNA synthetase, mitochondrial; AltName: Full=Lysine--tRNA ligase; Short=LysRS; Flags: Precursor [NCBI NR] gi\|3766370\|emb\|CAA21422.1\| mitochondrial lysine-tRNA ligase (predicted) [Schizosaccharomyces pombe] [NCBI NR] gi\|19075887\|ref\|NP_588387.1\| lysine-tRNA ligase [Schizosaccharomyces pombe] [NCBI NR] lysine-tRNA ligase [Sanger Pombe] Lysyl-tRNA synthetase, mitochondrial OS=Schizosaccharomyces pombe GN=msk1 PE=2 SV=1 [Swiss-Prot] LYSYL-TRNA SYNTHETASE, CYTOPLASMIC: O74858; [pompepVF.fasta] Lysyl-tRNA synthetase [pompep4896] \|\|\|lysyl-tRNA synthetase, cytoplasmic [pompepnew.fasta] SPCC18.08 protein [4896.FASTAC] \|\|\|lysine-tRNA ligase (predicted)\|Schizosaccharomyces pombe\|chr 3\|\|\|Manual [pombe041504.fasta] lysyl-trna synthetase [Schizosaccharomyces pombe]gi\|3766370\|emb\|CAA21422.1\| SPCC18.08 [Schizosaccharomyces pombe]gi\|7492144\|pir\|\|T41151 lysyl-trna synthetase - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas] \|\|\|lysine-tRNA ligase\|Schizosaccharomyces pombe\|chr 3\|\|\|Manual [pompep2242005.fasta] (O74858) Lysyl-tRNA synthetase [pompep4896_normal_reversed] \|\|\|mitochondrial lysine-tRNA ligase \|Schizosaccharomyces pombe\|chr 3\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] hypothetical protein SPCC18.08 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] SPCC18.08 [Schizosaccharomyces pombe] [nr-271106-contam.fasta] Lysine--tRNA ligase, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=msk1 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	531 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA][ISS]
Biological Process:	mitochondrial translation [RCA] lysyl-tRNA aminoacylation [ISS]
Molecular Function:	nucleic acid binding [ISS] ATP binding [ISS] lysine-tRNA ligase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISRGLLSKG ILSIIKRKNT GNLIPHVYYS EYHADIEERR KALGRLGISL YPSVTSDAST  60
   61 TTIPVIIEKW RNKITKSEIA MVRYTVCGRI SSIRYSGSKL AFFDVLYGNK KLQVVFNKKN 120
  121 IGTEEEMKGK FIPRLKALQK GDCIQCSGNV GRSGSGELSI YATELPKLLS PCLHPIPVKL 180
  181 TNYEKRFEKR FVDMMSNTKS LELLEKRYRI IESIRKFFSE RGFLEVETPI LSHHFGGATA 240
  241 RPFITSDIHK LPLTLRCAPE LWLKQLVIGG MNRVFELGKN FRNEGIDATH NPEFTSCEAY 300
  301 CAYLNLEGMK KLTEELIRFI CLTINGNLQI SGQTVDLEKG FEVIEFIPAL QKELNVELSP 360
  361 LDNSENCRKQ LISIFKRCEI MLPKTCTVAH LLDKLFDSLV LKYNTSSPKF VINHPEVMSP 420
  421 LAKSDIKLYG AVEQRISKRF ELYIGGYEIC NAYEEENDPV AQYHKFQAQK YDRLQLGDDE 480
  481 TPAPDSDFVH ALEYGLPPTA GWGMGVDRLV MLMTGQSKIS EILPFGSLRY V

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
lysine-tRNA ligase activity	5.79033103181143	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	3.53864660125764	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	3.53864660125764	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	3.52777284894652	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	2.99105702052936	bayes_pls_golite062009
nucleic acid binding	2.69275272183315	bayes_pls_golite062009
ligase activity	2.56279938346489	bayes_pls_golite062009
serine-tRNA ligase activity	2.46505535069103	bayes_pls_golite062009
structural constituent of ribosome	2.43759174701552	bayes_pls_golite062009
glycine-tRNA ligase activity	2.29229136935761	bayes_pls_golite062009
binding	2.20683882867211	bayes_pls_golite062009
threonine-tRNA ligase activity	2.18642354927	bayes_pls_golite062009
structural molecule activity	2.08258913217268	bayes_pls_golite062009
DNA binding	1.97161900822354	bayes_pls_golite062009
alanine-tRNA ligase activity	1.82594054955281	bayes_pls_golite062009
histidine-tRNA ligase activity	1.72215103383322	bayes_pls_golite062009
translation regulator activity	1.46320772716954	bayes_pls_golite062009
translation factor activity, nucleic acid binding	1.40718318783582	bayes_pls_golite062009
translation initiation factor activity	0.96756670903925	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.921774798819338	bayes_pls_golite062009
asparagine-tRNA ligase activity	0.921492123574877	bayes_pls_golite062009
structure-specific DNA binding	0.83085643154213	bayes_pls_golite062009
single-stranded DNA binding	0.56590887755068	bayes_pls_golite062009
transcription regulator activity	0.398606646713208	bayes_pls_golite062009
ribonuclease activity	0.305684604963838	bayes_pls_golite062009
protein binding	0.0528188351789111	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..531]	PSI-BLAST	141.0	Lysyl-tRNA synthetase (LysRS)

Protein Overview: SPCC18.08

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: