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Protein Overview: SPCC18.08

General Information:
Name(s) found: SPCC18.08 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • lysine-tRNA ligase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 531 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: mitochondrial translation [RCALink to PubMed article]
    lysyl-tRNA aminoacylation [ISSLink to PubMed article]
    Molecular Function: nucleic acid binding [ISSLink to PubMed article]
    ATP binding [ISSLink to PubMed article]
    lysine-tRNA ligase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISRGLLSKG ILSIIKRKNT GNLIPHVYYS EYHADIEERR KALGRLGISL YPSVTSDAST  60
   61 TTIPVIIEKW RNKITKSEIA MVRYTVCGRI SSIRYSGSKL AFFDVLYGNK KLQVVFNKKN 120
  121 IGTEEEMKGK FIPRLKALQK GDCIQCSGNV GRSGSGELSI YATELPKLLS PCLHPIPVKL 180
  181 TNYEKRFEKR FVDMMSNTKS LELLEKRYRI IESIRKFFSE RGFLEVETPI LSHHFGGATA 240
  241 RPFITSDIHK LPLTLRCAPE LWLKQLVIGG MNRVFELGKN FRNEGIDATH NPEFTSCEAY 300
  301 CAYLNLEGMK KLTEELIRFI CLTINGNLQI SGQTVDLEKG FEVIEFIPAL QKELNVELSP 360
  361 LDNSENCRKQ LISIFKRCEI MLPKTCTVAH LLDKLFDSLV LKYNTSSPKF VINHPEVMSP 420
  421 LAKSDIKLYG AVEQRISKRF ELYIGGYEIC NAYEEENDPV AQYHKFQAQK YDRLQLGDDE 480
  481 TPAPDSDFVH ALEYGLPPTA GWGMGVDRLV MLMTGQSKIS EILPFGSLRY V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..531] PSI-BLAST 141.0 Lysyl-tRNA synthetase (LysRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • lysine-tRNA ligase activity
    		•  5.79033103181143 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  3.53864660125764 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  3.53864660125764 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  3.52777284894652 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  2.99105702052936 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.69275272183315 bayes_pls_golite062009
  • ligase activity
    		•  2.56279938346489 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  2.46505535069103 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.43759174701552 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  2.29229136935761 bayes_pls_golite062009
  • binding
    		•  2.20683882867211 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  2.18642354927 bayes_pls_golite062009
  • structural molecule activity
    		•  2.08258913217268 bayes_pls_golite062009
  • DNA binding
    		•  1.97161900822354 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  1.82594054955281 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  1.72215103383322 bayes_pls_golite062009
  • translation regulator activity
    		•  1.46320772716954 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.40718318783582 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.96756670903925 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.921774798819338 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  0.921492123574877 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.83085643154213 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.56590887755068 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.398606646713208 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.305684604963838 bayes_pls_golite062009
  • protein binding
    		•  0.0528188351789111 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle