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Protein Overview: SPCC576.17c

General Information:
Name(s) found: SPCC576.17c [Sanger Pombe]
Description(s) found:
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  • pir||T41427 membrane transporter - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74626921|sp|O74899.1|YQEH_SCHPO RecName: Full=Uncharacterized transporter C576.17c [NCBI NR]
  • gi|3687472|emb|CAA21196.1| membrane transporter [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19075943|ref|NP_588443.1| membrane transporter [Schizosaccharomyces pombe] [NCBI NR]
  • membrane transporter [Sanger Pombe]
  • Uncharacterized transporter C576.17c OS=Schizosaccharomyces pombe GN=SPCC576.17c PE=1 SV=1 [Swiss-Prot]
  • MFS DRUG EFFLUX TRANSPORTER OF UNKNOWN SPECIFICITY: O74899; [pompepVF.fasta]
  • MFS drug efflux transporter of unknown specificity [pompep4896]
  • |||MFS drug efflux transporter of unknown specificity [pompepnew.fasta]
  • SPCC576.17c protein [4896.FASTAC]
  • |||transporter|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • MFS drug efflux transporter of unknown specificity [Schizosaccharomyces pombe]gi|3687472|emb|CAA21196.1| SPCC576.17c [Schizosaccharomyces pombe]gi|7492184|pir||T41427 membrane transporter - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • (O74899) MFS drug efflux transporter of unknown specificity [pompep4896_normal_reversed]
  • |||membrane transporter|Schizosaccharomyces pombe|chr 3|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPCC576.17c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPCC576.17c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • |||pyridoxamine/pyridoxine/pyridoxal transmembrane transporter |Schizosaccharomyces pombe|chr 3|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Uncharacterized transporter C576.17c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC576.17c PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 525 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [ISSLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    plasma membrane [ISSLink to PubMed article]
    Biological Process: pyridoxine transport [ISSLink to PubMed article]
    pyridoxamine transport [ISSLink to PubMed article]
    transmembrane transport [IEA]
    cellular response to stress [IEPLink to PubMed article]
    pyridoxal transport [ISSLink to PubMed article]
    Molecular Function: pyridoxamine transmembrane transporter activity [ISSLink to PubMed article]
    pyridoxine transmembrane transporter activity [ISSLink to PubMed article]
    pyridoxal transmembrane transporter activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDTNDVMHV HSESISPKKN DLDIELGESV VEPHLSNNSI AKLDTYELEE NEDISDYAYK  60
   61 LAGISNEHPA HPQNWGWWKK AYIVLLSTSL QMYVFWTPNF YPGVQDSVME LWHLSSQVSL 120
  121 LGQSMFVLGV ALGPLFLGPL SDLLGRKLVY IGSLIIYVCF CISCALARNY AQLVISMLIM 180
  181 GVVGSTALGN VAGAVADVLG DEDSNWGMYM FIFMCSVASV GSPMGTGVAE NPKLTWRWLY 240
  241 WIDVIVGGFF IILFVFTPET LPAIVIQRYE QKRQGLPVSW FPQFSLKKLA KDTYFVFFMA 300
  301 IKIFFSEPIV SSLGIYNGFV NGLLYFFLQA IWPVYFSIYK MSDMAASCTY MAAMPACVIL 360
  361 LWFEPLQCWL YKRDKRKHQN RLRPEARFIM TLFYVWGFPI GIFMFAFCSK VHIHYIVSLI 420
  421 GLTIFNIADY HIWQAMLLYV TDAYPNVSAS AVAAFELPSN LGAVGFIHLS ALMFSRMNVH 480
  481 WATAVVGFAS LPLIALIYAL YFYGDRIRAR SKLASQRVPI NTAAH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..525] PSI-BLAST 29.69897 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  3.18173622457291 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  3.18173622457291 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  2.63293544825311 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  1.24937104052238 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • binding
    		•  1.01584233411372 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle