YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC576.17c
Organism:	Schizosaccharomyces pombe
Length:	525 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC576.17c.

Description	E-value	Query Range	Subject Range
gi\|49072098, gi\|... - gi\|71016129\|ref\|XP_758870.1\| hypothetical protein UM02723.1 [Ustilago maydis 521], ref\|XP_400338.1\| ...	238.0	[0..7]	[516..101]
gi\|70984531, gi\|... - gi\|70984531\|ref\|XP_747772.1\| MFS multidrug transporter [Aspergillus fumigatus Af293], gi\|66845399\|gb... gi\|159122556 - gi\|159122556\|gb\|EDP47677.1\| MFS multidrug transporter, putative [Aspergillus fumigatus A1163]	237.0	[0..28]	[515..113]
gi\|39944294, gi\|... - gi\|39944294\|ref\|XP_361684.1\| hypothetical protein MGG_04158 [Magnaporthe grisea 70-15], gb\|EAA50399....	223.0	[0..4]	[514..50]
gi\|88184223, gi\|... - gi\|88184223\|gb\|EAQ91691.1\| hypothetical protein CHGG_03626 [Chaetomium globosum CBS 148.51], gi\|1162...	220.0	[0..4]	[461..106]
gi\|49650092 - gi\|49650092\|emb\|CAG79818.1\| YALI0E21241p [Yarrowia lipolytica] gi\|49650092, gi\|... - gi\|50553624\|ref\|XP_504223.1\| YALI0E21241p [Yarrowia lipolytica], gi\|49650092\|emb\|CAG79818.1\| unnamed...	220.0	[0..14]	[522..67]
gi\|42554903, gi\|... - gi\|46136363\|ref\|XP_389873.1\| hypothetical protein FG09697.1 [Gibberella zeae PH-1], gi\|42554903\|gb\|E...	219.0	[0..3]	[521..40]
gi\|67668083, gi\|... - gi\|67668083\|ref\|ZP_00465278.1\| General substrate transporter:Major facilitator superfamily [Burkhold...	213.0	[0..40]	[515..1002]
gi\|68471725, gi\|... - gi\|68471986\|ref\|XP_720036.1\| potential drug or polyamine transporter [Candida albicans SC5314], gi\|6... orf19.7974, orf1... - orf19.341 CGDID:CAL0004786 Assembly 19, Contig19-10046 (202026, 200095) CDS, reverse complemented, t...	211.0	[0..57]	[524..152]
YCT4_SCHPO - Uncharacterized transporter C794.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC7... SPCC794.04c - membrane transporter	209.0	[0..2]	[514..36]
gi\|40745169, gi\|... - gi\|67904012\|ref\|XP_682262.1\| hypothetical protein AN8993.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	208.0	[0..50]	[511..7]

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Predicted Domain #1

Region A:
Residues: [1-525]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDTNDVMHV HSESISPKKN DLDIELGESV VEPHLSNNSI AKLDTYELEE NEDISDYAYK  60
   61 LAGISNEHPA HPQNWGWWKK AYIVLLSTSL QMYVFWTPNF YPGVQDSVME LWHLSSQVSL 120
  121 LGQSMFVLGV ALGPLFLGPL SDLLGRKLVY IGSLIIYVCF CISCALARNY AQLVISMLIM 180
  181 GVVGSTALGN VAGAVADVLG DEDSNWGMYM FIFMCSVASV GSPMGTGVAE NPKLTWRWLY 240
  241 WIDVIVGGFF IILFVFTPET LPAIVIQRYE QKRQGLPVSW FPQFSLKKLA KDTYFVFFMA 300
  301 IKIFFSEPIV SSLGIYNGFV NGLLYFFLQA IWPVYFSIYK MSDMAASCTY MAAMPACVIL 360
  361 LWFEPLQCWL YKRDKRKHQN RLRPEARFIM TLFYVWGFPI GIFMFAFCSK VHIHYIVSLI 420
  421 GLTIFNIADY HIWQAMLLYV TDAYPNVSAS AVAAFELPSN LGAVGFIHLS ALMFSRMNVH 480
  481 WATAVVGFAS LPLIALIYAL YFYGDRIRAR SKLASQRVPI NTAAH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.69897
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.54194478414824	bayes_pls_golite062009
hexose phosphate transmembrane transporter activity	3.18173622457291	bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity	3.18173622457291	bayes_pls_golite062009
sugar:hydrogen symporter activity	2.99050613058546	bayes_pls_golite062009
cation:sugar symporter activity	2.99050613058546	bayes_pls_golite062009
monosaccharide transmembrane transporter activity	2.63293544825311	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	2.62141276633776	bayes_pls_golite062009
sugar transmembrane transporter activity	2.47557586092261	bayes_pls_golite062009
ion transmembrane transporter activity	2.21266150105753	bayes_pls_golite062009
solute:hydrogen symporter activity	2.10485633822652	bayes_pls_golite062009
cation transmembrane transporter activity	1.79369588808394	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
organic acid transmembrane transporter activity	1.24937104052238	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
binding	1.01584233411372	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: