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Protein Overview: rct1

General Information:
Name(s) found: rct1 / SPBC17G9.05 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • RRM-containing cyclophilin regulating transcription Rct1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 432 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    Biological Process: cell morphogenesis [IMPLink to PubMed article]
    protein folding [TASLink to PubMed article]
    RNA elongation from RNA polymerase II promoter [IMPLink to PubMed article]
    Molecular Function: peptidyl-prolyl cis-trans isomerase activity [ISSLink to PubMed article]
    RNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVLIETTVG DLVIDLFVKE APKTCENFLK LCKLKYYNFC PFYNIQHNYT CQTGDPLGPT  60
   61 GDGGRCVWNV LNKGTRFFKA EFNPSLVHNK MGLVSMSTAT ISSRDDKLLV CGSQFIITLS 120
  121 DNLEGLDERY PIYGQVAEGF DTLLKINDAI CDEEGQPYRD IRIKHTIILD DPFEDPPDLV 180
  181 EPLRSPSPTP EQLATVRIGE NEQIESETSE DKLQREKEME AEAEAVTLEM IGDLPFAHVA 240
  241 PPENVLFVCK LNPVTQDEDL ELIFSRFGKI ISCQVIRDKE TGDSLQYAFI EFDNKESVEK 300
  301 AYFKMQNVLI DDSRIHVDFS QSVARYRQYY NSNRDRKRSS SRSDDREYHR RSDGRYDRSN 360
  361 YRDDYRHRRK ERDHRDDQSS FRNERFSNYY GDDRSYHKRR NTGNKNCDDH LRDKSPERRY 420
  421 RYDRRYRDDR YR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..154] PSI-BLAST 18.69897 Crystal Structure of Recombinant Human Cyclophilin J
    2 View Details [155..325] PSI-BLAST 29.0 Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
    3 View Details [326..432] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidyl-prolyl cis-trans isomerase activity
    		•  3.73853378771688 bayes_pls_golite062009
  • cis-trans isomerase activity
    		•  3.66963215732405 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.0418369369681 bayes_pls_golite062009
  • isomerase activity
    		•  1.96529188741504 bayes_pls_golite062009
  • binding
    		•  1.65866393331484 bayes_pls_golite062009
  • unfolded protein binding
    		•  1.38124355054041 bayes_pls_golite062009
  • catalytic activity
    		•  0.748655649755714 bayes_pls_golite062009
  • protein binding
    		•  0.230077752280113 bayes_pls_golite062009
    2
    Term Confidence Notes
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • RNA binding
    		•  2.92438188845619 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.71887087575948 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • DNA binding
    		•  1.98418556946403 bayes_pls_golite062009
  • mRNA binding
    		•  1.94495589345842 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription factor activity
    		•  1.07843408116687 bayes_pls_golite062009
    		• 0.84116054461637 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  0.764897709725891 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.632534695085793 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
  • structural molecule activity
    		•  0.347575413104581 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle