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Protein Overview: mst1

General Information:
Name(s) found: mst1 / SPAC637.12c [Sanger Pombe]
Description(s) found:
Found 22 descriptions.
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  • histone acetyltransferase Mst1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 463 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    nuclear chromatin [IDALink to PubMed article]
    NuA4 histone acetyltransferase complex [IDALink to PubMed article]
    Biological Process: histone H4 acetylation [ISSLink to PubMed article]
    centromere complex assembly [IGILink to PubMed article]
    chromatin remodeling [RCALink to PubMed article]
    replication fork protection [IGILink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    chromatin assembly or disassembly [IEA]
    regulation of transcription [IEA]
    double-strand break repair [IGILink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    chromatin binding [IEA]
    H4 histone acetyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNDVDDESK IETKSYEAKD IVYKSKVFAF KDGEYRKAEI LMIQKRTRGV VYYVHYNDYN  60
   61 KRLDEWITID NIDLSKGIEY PPPEKPKKAH GKGKSSKRPK AVDRRRSITA PSKTEPSTPS 120
  121 TEKPEPSTPS GESDHGSNAG NESLPLLEED HKPESLSKEQ EVERLRFSGS MVQNPHEIAR 180
  181 IRNINKICIG DHEIEPWYFS PYPKEFSEVD IVYICSFCFC YYGSERQFQR HREKCTLQHP 240
  241 PGNEIYRDDY ISFFEIDGRK QRTWCRNICL LSKLFLDHKM LYYDVDPFLF YCMCRRDEYG 300
  301 CHLVGYFSKE KESSENYNLA CILTLPQYQR HGYGKLLIQF SYELTKREHK HGSPEKPLSD 360
  361 LGLISYRAYW AEQIINLVLG MRTETTIDEL ANKTSMTTND VLHTLQALNM LKYYKGQFII 420
  421 CISDGIEQQY ERLKNKKRRR INGDLLADWQ PPVFHPSQLR FGW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..171] PSI-BLAST 16.69897 Solution Structure of the Tudor Domain from Mouse Hypothetical Protein Homologous to Histone Acetyltransferase
    2 View Details [172..463] PSI-BLAST 126.0 Histone acetyltransferase ESA1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription repressor activity
    		•  4.08500855631983 bayes_pls_golite062009
  • chromatin binding
    		•  3.84065302930105 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.64390820819794 bayes_pls_golite062009
  • methylated histone residue binding
    		•  3.42338304360938 bayes_pls_golite062009
  • binding
    		•  3.06758476214113 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  2.46353586381231 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.19167058827256 bayes_pls_golite062009
  • DNA binding
    		•  2.05514577638135 bayes_pls_golite062009
  • histone binding
    		•  2.00388175060339 bayes_pls_golite062009
  • protein binding
    		•  1.61683263008775 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.998957812785999 bayes_pls_golite062009
  • general transcriptional repressor activity
    		•  0.75184432495983 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.726970683178132 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.494788451379878 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.294457188332415 bayes_pls_golite062009
  • catalytic activity
    		•  0.14067200158938 bayes_pls_golite062009
  • transcription activator activity
    		•  0.136090220479238 bayes_pls_golite062009
    2
    Term Confidence Notes
  • N-acetyltransferase activity
    		•  10.330867741687 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  10.2385402730839 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  10.2385402730839 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  10.2097972775096 bayes_pls_golite062009
  • acetyltransferase activity
    		•  9.5414870492393 bayes_pls_golite062009
  • acyltransferase activity
    		•  8.84144467104026 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  8.80032457938662 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  8.58458341779614 bayes_pls_golite062009
    		• 7.30820970670781 bayes_pls_golite062009
    		• 5.22897636875434 bayes_pls_golite062009
  • H3 histone acetyltransferase activity
    		•  3.57980162499154 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.87587084880956 bayes_pls_golite062009
  • transferase activity
    		•  2.87429355361226 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.24760844790231 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.13750665291344 bayes_pls_golite062009
  • catalytic activity
    		•  1.97933499002461 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.31507488567214 bayes_pls_golite062009
  • binding
    		•  1.22537494136129 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.2180007740195 bayes_pls_golite062009
  • transcription factor binding
    		•  1.13174003342838 bayes_pls_golite062009
  • transcription activator activity
    		•  0.891911076312861 bayes_pls_golite062009
  • glycylpeptide N-tetradecanoyltransferase activity
    		•  0.774009286200155 bayes_pls_golite062009
  • myristoyltransferase activity
    		•  0.774009286200155 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.605899196605446 bayes_pls_golite062009
  • histone binding
    		•  0.582104626133107 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.31196049232138 bayes_pls_golite062009
  • protein binding
    		•  0.075825416385311 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle