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Protein Overview: SPAC11E3.05

General Information:
Name(s) found: SPAC11E3.05 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • ubiquitin-protein ligase E3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1323 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole membrane [ISSLink to PubMed article]
    protein complex [RCALink to PubMed article]
    Biological Process: protein ubiquitination [ISSLink to PubMed article]
    Molecular Function: ubiquitin-protein ligase activity [ISSLink to PubMed article]
    zinc ion binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRELQGDDSS RKSPPSDSVV KNSSPIDYEH SLKSLQDERT LNYPNKQFNS ENPSSYYNMD  60
   61 DSGELCNFEL EKDSLESMIH ESSTALSAQS NTAQDGDQLA SSSTISKDHS ETLDNKLNDS 120
  121 KILIKKASNS FANFSESVRS STIVAYSQTP TQRLQGLTSI SSSSFDDGSY GSRRISFNSQ 180
  181 GVSGRLRRNM DSTVIIPSED EDLQLPSNSN SNVEYGPFDS TTFDRQLSIE VNQPVGAMSL 240
  241 SPCGRDIALA SRYGLLVLDL DNPYNPPRML RHSTPWEVAD TQWNVHAARD QWVVSTSSQK 300
  301 TIVWNLALPN DRAIEFMLHG HTRAVTDMNW HRQNPDVLAT CSIDSSVHCW DLRSPRFPVN 360
  361 SFYDWHNGAT QVKWNYKNPH ILASSHGRLV RIWDDRYGSA PLHTIKTSEN ITKINGLEFN 420
  421 RACETRLLTC AMDRTVKFWN YEKSTEEPEH LITTDSPVWK ARFTPFGDGV ILMPQRGDNS 480
  481 VHMYDCRNLD KEGPRAVHRF AGHTDQVKEF LWRCRGEDVF DRDLRDFQLI TWSKDHHVRL 540
  541 WPIGNDILNS MGHDRTKPVP FKLTRLGAKY RTYSREPLKQ SLINTECDSS DAMNSFDSNF 600
  601 GAERANTSDL SRGFVAFANR KKSKYNLPGS SGFMTRSTKS TNPMTPLNWL RGISMGRLGN 660
  661 ADWEVPQNLG EELSWIGQKY SNVSFEKIDV AERTCTISLN APILPDDGYA YIRLHVYFPN 720
  721 NYPISATPVF QLERSSAFND EQFNYVFNTL TSISDQCISS HKYCMDACLS YLSGNLSVDE 780
  781 IWKLGFQKDN SDSSSESSAD IFQDVFPSMP DFRGGDRGLS HKHQNIPLPK TCAAIFCGND 840
  841 ELVCFFTIKA DESAAQATAN RETHGRQKLF ESFGVLDSSN SVADSDSTNY DDENSLNRGG 900
  901 TSESDSEFIW DVDESNSGSI VFPKSKTSIN LNNINSASAS IMGSRFGAAD IFMSKRPSTK 960
  961 GSNRPSILLS KPSHDFHVVR IISMSKYLPV KRALAAEYVV DTGDKVTVCN KNAEVSAKHN1020
 1021 YYRLAKVWLM LGRLLGHLSR TENKDHINDE EAFPWLKSPL AKWVVNSLLD YYASQCNTQM1080
 1081 LAMLACVLDI PNPKKQSGNT SADQVLFNQP KQVTEKLGVQ LNLPKTKILE KVSSHSLAQI1140
 1141 TALREKEPKD ADSTYSKEKI FSATSTVHLQ LMDYDKQNND FVDAQEIAYT KLLQQKFIQW1200
 1201 RATYAEQLDL WGFFIPKLEM LKFNAHEFSS PSEKTLVNHC NSCNSTTSNT RICEKCYSLV1260
 1261 PRMSCTFCCL SIHGLCIVCG LCLHVMHEDC YKEWFSNGDS ISQSCSSGCG CKCQFQHMSL1320
 1321 EKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..107] PSI-BLAST 5.522879 No description for 2ojhA was found.
    2 View Details [108..485] PSI-BLAST 57.69897 No description for 2ovpB was found.
    3 View Details [486..636] PSI-BLAST 64.0 PAF-AH Holoenzyme: Lis1/Alfa2
    4 View Details [637..868] FFAS03 1.19 No description for 2daxA was found.
    5 View Details [869..948] deduced N/A No confident structure predictions are available.
    6 View Details [949..1172] deduced N/A No confident structure predictions are available.
    7 View Details [1173..1323] FFAS03 1.84 No description for 2ep4A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  5.92248163880907 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  5.9086319430991 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  5.0261946125134 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  3.408033340951 bayes_pls_golite062009
  • ligase activity
    		•  1.54502300784947 bayes_pls_golite062009
  • catalytic activity
    		•  0.843965854182766 bayes_pls_golite062009
  • protein binding
    		•  0.838850681576122 bayes_pls_golite062009
  • binding
    		•  0.756713779508906 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  0.259607886535948 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.158224176330677 bayes_pls_golite062009
  • protein kinase activity
    		•  0.156381916938112 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.140898268391068 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.114161137460685 bayes_pls_golite062009
  • kinase activity
    		•  0.0626237835448453 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle