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Protein Overview: SPAC1296.06

General Information:
Name(s) found: SPAC1296.06 [Sanger Pombe]
Description(s) found:
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  • pir||T37567 probable NADPH cytochrome reductase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74582946|sp|O94613.1|TAH18_SCHPO RecName: Full=Probable NADPH reductase TAH18 [NCBI NR]
  • gi|4500377|emb|CAB36512.2| NADPH-dependent diflavin oxidoreductase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113958|ref|NP_593046.1| NADPH cytochrome reductase [Schizosaccharomyces pombe] [NCBI NR]
  • NADPH cytochrome reductase [Sanger Pombe]
  • Probable NADPH reductase TAH18 OS=Schizosaccharomyces pombe GN=tah18 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE NADPH CYTOCHROME REDUCTASE: O94613; [pompepVF.fasta]
  • Putative NADPH cytochrome reductase (EC 1.6.2.4) [pompep4896]
  • |||putative NADPH cytochrome reductase [pompepnew.fasta]
  • SPAC1296.06 protein (EC 1.6.2.4) [4896.FASTAC]
  • |||NADPH cytochrome reductase|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative NADPH cytochrome reductase [Schizosaccharomyces pombe]gi|4500377|emb|CAB36512.2| SPAC1296.06 [Schizosaccharomyces pombe]gi|7492751|pir||T37567 probable NADPH cytochrome reductase - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • (O94613) Putative NADPH cytochrome reductase (EC 1.6.2.4) [pompep4896_normal_reversed]
  • |||NADPH-dependent diflavin oxidoreductase |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPAC1296.06 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPAC1296.06 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Probable NADPH reductase TAH18 [nr-271106-contam.fasta]
    • Organism: Schizosaccharomyces pombe
    Length: 558 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: NADP or NADPH binding [ISS]
    FMN binding [ISS]
    FAD binding [ISS]
    oxidoreductase activity [ISS]
    iron ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNSHIYILY GSETGTAEGL AESLFRSLTR MGYDVLVNSM DDFNLENLLR PLQCVFICST  60
   61 TGQGEMPLNM RERIITYRFN WASKKLDSRL RQLGAQSFSS RGEGDEQHPD GVEGVFAYWC 120
  121 NHLYSQLAAI KTPSRPAFGE FDLLPPSFQI IIDESLGCKV KGFEDNNIVR HSRGKIEATL 180
  181 VHNKRISNIK HWQDVRHLAF KIPNFERWKP GDVAVLYPWN DDMSVNSFIE CMGWESIKYS 240
  241 PLIISSNVAE RKLPWFPNIL NVFNLVKYVL SIHSVPSRTF FEMASHFSNN KMHKERLQEF 300
  301 SSYKNIDDYY DYTTRPRRTV LETLQEFKSV QIPIEYALDA FPVIRGRQYS IANRCDNSTG 360
  361 ILELAVALVK YQTILKSPRQ GICSRWICDL HENTSFNIDI LPGFLNLSYQ SNKPLIMVGP 420
  421 GTGVAPLRAL IQERIYNGLK ENLLFFGCRN KSMDFLFEKD WEKYTEEGTL KLFCAFSRDQ 480
  481 EKKKYVQHSI QENGELVYNL LNEKDGMFFV SGSSGKMPSS VKDAIAGIVS KYSGCSISDG 540
  541 YSFVTSLEKK NRYYQETW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..558] PSI-BLAST 116.0 NADPH-cytochrome p450 reductase; NADPH-cytochrome p450 reductase, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • sulfite reductase (NADPH) activity
    		•  8.084406223553 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
    		•  4.30314846685644 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  4.19887641848781 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  4.06091555929351 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  3.8525097290463 bayes_pls_golite062009
  • coenzyme binding
    		•  3.33805077160148 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor
    		•  3.111558299994 bayes_pls_golite062009
  • NADH dehydrogenase activity
    		•  3.09973680094998 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  3.01705400717654 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  2.84592668144284 bayes_pls_golite062009
  • FAD binding
    		•  2.07600122867642 bayes_pls_golite062009
  • cytochrome-b5 reductase activity
    		•  1.5685421124725 bayes_pls_golite062009
  • cofactor binding
    		•  1.53717310937468 bayes_pls_golite062009
  • ferredoxin reductase activity
    		•  1.46342400843015 bayes_pls_golite062009
  • ferredoxin-NADP+ reductase activity
    		•  1.46342400843015 bayes_pls_golite062009
  • oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor
    		•  1.46342400843015 bayes_pls_golite062009
  • catalytic activity
    		•  1.45374095556065 bayes_pls_golite062009
  • binding
    		•  1.33256635332573 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.32610551863387 bayes_pls_golite062009
  • monooxygenase activity
    		•  1.24895114339483 bayes_pls_golite062009
  • NADP or NADPH binding
    		•  1.18833847639357 bayes_pls_golite062009
  • demethylase activity
    		•  1.1768217851058 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  1.11231803143399 bayes_pls_golite062009
  • oxidoreductase activity, acting on iron-sulfur proteins as donors
    		•  0.73475657802914 bayes_pls_golite062009
  • transferase activity
    		•  0.708491789248912 bayes_pls_golite062009
  • FMN binding
    		•  0.649158247260553 bayes_pls_golite062009
  • riboflavin synthase activity
    		•  0.380537461428523 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.27336340260908 bayes_pls_golite062009
  • protein binding
    		•  0.244726474314668 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle