YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC1296.06
Organism:	Schizosaccharomyces pombe
Length:	558 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC1296.06.

Description	E-value	Query Range	Subject Range
NCPR_PIG - NADPH--cytochrome P450 reductase OS=Sus scrofa GN=POR PE=1 SV=2	428.0	[0..3]	[558..77]
gi\|110759146 - gi\|110759146\|ref\|XP_001119949.1\| PREDICTED: similar to NADPH--cytochrome P450 reductase (CPR) (P450R...	426.0	[0..2]	[558..95]
NCPR_CAVPO - NADPH--cytochrome P450 reductase OS=Cavia porcellus GN=Por PE=2 SV=2	423.0	[0..3]	[558..77]
gi\|108881172, gi... - gi\|157135880\|ref\|XP_001656715.1\| nadph cytochrome P450 [Aedes aegypti], gi\|108881172\|gb\|EAT45397.1\| ...	421.0	[0..2]	[558..79]
gi\|50758116 - gi\|50758116\|ref\|XP_415768.1\| PREDICTED: similar to MGC69029 protein [Gallus gallus]	421.0	[0..3]	[558..291]
gi\|37590720, gi\|... - gi\|37590720\|gb\|AAH59318.1\| Npr protein [Xenopus laevis], gi\|148223907\|ref\|NP_001078953.1\| NADPH-P450...	421.0	[0..3]	[558..80]
gi\|1296517 - gi\|1296517\|emb\|CAA63639.1\| NADPH--ferrihemoprotein reductase; NADPH-cytochrome P450 reductase [Droso...	419.0	[0..2]	[558..80]
gi\|78369374, gi\|... - gi\|78369374\|ref\|NP_001030467.1\| cytochrome P450 reductase [Bos taurus], gi\|74268199\|gb\|AAI03400.1\| C...	419.0	[0..3]	[558..79]

Back

Predicted Domain #1

Region A:
Residues: [1-558]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNSHIYILY GSETGTAEGL AESLFRSLTR MGYDVLVNSM DDFNLENLLR PLQCVFICST  60
   61 TGQGEMPLNM RERIITYRFN WASKKLDSRL RQLGAQSFSS RGEGDEQHPD GVEGVFAYWC 120
  121 NHLYSQLAAI KTPSRPAFGE FDLLPPSFQI IIDESLGCKV KGFEDNNIVR HSRGKIEATL 180
  181 VHNKRISNIK HWQDVRHLAF KIPNFERWKP GDVAVLYPWN DDMSVNSFIE CMGWESIKYS 240
  241 PLIISSNVAE RKLPWFPNIL NVFNLVKYVL SIHSVPSRTF FEMASHFSNN KMHKERLQEF 300
  301 SSYKNIDDYY DYTTRPRRTV LETLQEFKSV QIPIEYALDA FPVIRGRQYS IANRCDNSTG 360
  361 ILELAVALVK YQTILKSPRQ GICSRWICDL HENTSFNIDI LPGFLNLSYQ SNKPLIMVGP 420
  421 GTGVAPLRAL IQERIYNGLK ENLLFFGCRN KSMDFLFEKD WEKYTEEGTL KLFCAFSRDQ 480
  481 EKKKYVQHSI QENGELVYNL LNEKDGMFFV SGSSGKMPSS VKDAIAGIVS KYSGCSISDG 540
  541 YSFVTSLEKK NRYYQETW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	116.0
Match:	1amoA
Description:	NADPH-cytochrome p450 reductase; NADPH-cytochrome p450 reductase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
sulfite reductase (NADPH) activity	8.084406223553	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	4.30314846685644	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	4.19887641848781	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	4.06091555929351	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	3.8525097290463	bayes_pls_golite062009
coenzyme binding	3.33805077160148	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor	3.111558299994	bayes_pls_golite062009
NADH dehydrogenase activity	3.09973680094998	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	3.01705400717654	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	2.84592668144284	bayes_pls_golite062009
FAD binding	2.07600122867642	bayes_pls_golite062009
cytochrome-b5 reductase activity	1.5685421124725	bayes_pls_golite062009
cofactor binding	1.53717310937468	bayes_pls_golite062009
ferredoxin reductase activity	1.46342400843015	bayes_pls_golite062009
ferredoxin-NADP+ reductase activity	1.46342400843015	bayes_pls_golite062009
oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor	1.46342400843015	bayes_pls_golite062009
catalytic activity	1.45374095556065	bayes_pls_golite062009
binding	1.33256635332573	bayes_pls_golite062009
transcription regulator activity	1.32610551863387	bayes_pls_golite062009
monooxygenase activity	1.24895114339483	bayes_pls_golite062009
NADP or NADPH binding	1.18833847639357	bayes_pls_golite062009
demethylase activity	1.1768217851058	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	1.11231803143399	bayes_pls_golite062009
oxidoreductase activity, acting on iron-sulfur proteins as donors	0.73475657802914	bayes_pls_golite062009
transferase activity	0.708491789248912	bayes_pls_golite062009
FMN binding	0.649158247260553	bayes_pls_golite062009
riboflavin synthase activity	0.380537461428523	bayes_pls_golite062009
oxidoreductase activity	0.27336340260908	bayes_pls_golite062009
protein binding	0.244726474314668	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: