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Protein Overview: SPBC83.17

General Information:
Name(s) found: SPBC83.17 [Sanger Pombe]
Description(s) found:
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  • pir||T40706 yeast mbf1 homolog, transcription factor - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|73621197|sp|O94700.1|MBF1_SCHPO RecName: Full=Multiprotein-bridging factor 1 [NCBI NR]
  • gi|4455790|emb|CAB36879.1| transcriptional coactivator, multiprotein bridging factor Mbf1 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112442|ref|NP_595650.1| transcriptional coactivator, multiprotein bridging factor Mbf1 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • transcriptional coactivator, multiprotein bridging factor Mbf1 [Sanger Pombe]
  • Multiprotein-bridging factor 1 OS=Schizosaccharomyces pombe GN=mbf1 PE=2 SV=1 [Swiss-Prot]
  • TRANSCRIPTION FACTOR; SIMILAR TO S. CEREVISIAE MBF1: O94700; [pompepVF.fasta]
  • YEAST MBF1 HOMOLOG, TRANSCRIPTION FACTOR: O94700; [pompepV13]
  • Yeast mbf1 homolog, transcription factor [pompep4896]
  • |||transcription factor [pompepnew.fasta]
  • SPBC83.17 protein [4896.FASTAC]
  • |||transcription factor|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • yeast mbf1 homolog, transcription factor [Schizosaccharomyces pombe]gi|4455790|emb|CAB36879.1| SPBC83.17 [Schizosaccharomyces pombe]gi|7493730|pir||T40706 yeast mbf1 homolog, transcription factor - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • (O94700) Yeast mbf1 homolog, transcription factor [pompep4896_normal_reversed]
  • |||transcriptional coactivator, multiprotein bridging factor Mbf1 |Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • transcription factor protein [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC83.17 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Multiprotein-bridging factor 1 [nr-271106-contam.fasta]
  • Multiprotein-bridging factor 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mbf1 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 148 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    nucleolus [IDALink to PubMed article]
    Biological Process: positive regulation of transcription from RNA polymerase II promoter [ISSLink to PubMed article]
    positive regulation of gene-specific transcription from RNA polymerase II promoter [NAS]
    Molecular Function: DNA binding [ISSLink to PubMed article]
    transcription coactivator activity [ISSLink to PubMed article]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDWDTVTKI GSRAGPGART HVAKTQSQIN SARRAGAIVG TEKKYATGNK SQDPAGQHLT  60
   61 KIDRENEVKP PSTTGRSVAQ AIQKGRQAKG WAQKDLSQRI NEKPQVVNDY ESGRAIPNQQ 120
  121 VLSKMERALG IKLRGQNIGA PLGGPKKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..69] Pfam 32.769551 No description for PF08523.1 was found. No confident structure predictions are available.
    2 View Details [70..148] PSI-BLAST 8.09691 Solution structures of the HTH domain of human EDF-1 protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • DNA binding
    		•  5.51228466689923 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.37468811865033 bayes_pls_golite062009
  • transcription regulator activity
    		•  5.05236457497789 bayes_pls_golite062009
  • transcription factor activity
    		•  3.89464979825638 bayes_pls_golite062009
  • binding
    		•  3.66501723413351 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.25218945600666 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22754992035091 bayes_pls_golite062009
  • transcription activator activity
    		•  3.15886611325686 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.75958281319075 bayes_pls_golite062009
  • protein binding
    		•  1.55649304400241 bayes_pls_golite062009
  • chromatin binding
    		•  1.2739759748489 bayes_pls_golite062009
  • transcription factor binding
    		•  1.02788976342343 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.92393807212912 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.8718993114781 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.81316180547536 bayes_pls_golite062009
  • hydrolase activity
    		•  0.705005414525139 bayes_pls_golite062009
  • promoter binding
    		•  0.22765608166458 bayes_pls_golite062009
  • catalytic activity
    		•  0.00446472034106909 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle