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Protein Overview: sfc6

General Information:
Name(s) found: sfc6 / SPBC21H7.05 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • transcription factor TFIIIC complex subunit Sfc6 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 582 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    transcription factor TFIIIC complex [IDALink to PubMed article]
    Biological Process: transcription initiation from RNA polymerase III promoter [IDALink to PubMed article]
    regulation of transcription [ICLink to PubMed article]
    Molecular Function: chromatin insulator sequence binding [IDALink to PubMed article]
    RNA polymerase III transcription factor activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPKSKEYEN PSSYKNDEDN DDDGDFVLEN VMSEEDIEIE TPSRNRKRVS TTRRTPSKPI  60
   61 RSQPLTPSSS KGAGNEPKSQ NSSTTRGSAK KQSSKGLEEK LINSYGTHVE SLNKGRRLIE 120
  121 IWKYYETAPG QSSFEGQTSS DSKLQTLLNL DGQQLLSYSE NPFYLFEVKN LSISFHFESP 180
  181 QQVEPCQPVN PFKENPQKSG FVVNTGIPLS SVSWLPTNKE TQFLAVGGML KFSETTESVF 240
  241 MRTSGRNQIQ LWKLENKTNF KSEFILYHDW GSVLQLEWCP TISVEDSILG FLAVVCSDGK 300
  301 LRVLRVPRSP VKFHVFVEQA DFTFGFNDSL ISCCTWVSPE HGDIHQILVG CSNGYLALWD 360
  361 ILSSQECPLF YIPYHDSYIH NVVQCLDDFP WLFLTTAFDC YTRIFDIRDP IIDNRPLSHK 420
  421 RDICYTITWN NMLQSIISCS ESQSVVIESL RGTSTQLLDE RNGSIISLSN SKFHPFVACA 480
  481 ASDGIVTIVN PFRLLGFSHK QKANVHRIFQ LEYSEKQDSY RMLDGFRPRL PKAKKLDMYI 540
  541 YPWQIQVNKV EWNGNKGYAG WLASGMACGI LRVEDLSAVE RR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..500] PSI-BLAST 32.221849 Actin interacting protein 1
    2 View Details [501..582] PSI-BLAST 24.69897 No description for 2pm6B was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  3.30602815841673 bayes_pls_golite062009
  • binding
    		•  2.94886969723315 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.3610959773142 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.89191344969218 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  1.47917368317999 bayes_pls_golite062009
  • DNA binding
    		•  1.4719281452238 bayes_pls_golite062009
  • protein binding
    		•  1.42618832381942 bayes_pls_golite062009
  • transcription factor activity
    		•  0.883016478133271 bayes_pls_golite062009
    		• 0.88172763425403 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.658573452658359 bayes_pls_golite062009
  • transcription factor binding
    		•  0.489473003915035 bayes_pls_golite062009
  • snoRNA binding
    		•  0.347797037104681 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30761651528651 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.0532675540353509 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle