Protein Overview: tfg2

General Information:
Name(s) found:	tfg2 / SPBC1198.13c [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	gi\|7801320\|emb\|CAB91188.1\| transcription factor TFIIF complex beta subunit Tfg2 (predicted) [Schizosaccharomyces pombe] [NCBI NR] pir\|\|T40615 transcription initiation factor iif, beta subunit - fission yeast (Schizosaccharomyces pombe) [NCBI NR] gi\|74582884\|sp\|O94424.1\|T2FB_SCHPO RecName: Full=Transcription initiation factor IIF subunit beta; AltName: Full=ATP-dependent helicase TFG2; AltName: Full=TFIIF-beta; AltName: Full=TFIIF medium subunit [NCBI NR] gi\|4049502\|emb\|CAA22523.1\| SPBC660.03c [Schizosaccharomyces pombe] [NCBI NR] gi\|19111874\|ref\|NP_595082.1\| transcription factor TFIIF complex beta subunit Tfg2 (predicted) [Schizosaccharomyces pombe] [NCBI NR] transcription factor TFIIF complex beta subunit Tfg2 [Sanger Pombe] Transcription initiation factor IIF subunit beta OS=Schizosaccharomyces pombe GN=tfg2 PE=1 SV=1 [Swiss-Prot] TRANSCRIPTION INITIATION FACTOR TFIIF, BETA SUBUNIT: O94424; [pompepVF.fasta] TRANSCRIPTION INITIATION FACTOR IIF, BETA SUBUNIT TRANSCRIPTION INITIATION FACTOR TFIIF, BETA SUBUNIT: O94424; [pompepV13] Transcription initiation factor IIF, beta subunit [pompep4896] \|\|SPBC660.03c\|putative transcription initiation factor TFIIF, beta subunit [pompepnew.fasta] SPBC660.03c protein (SPBC1198.13c protein) [4896.FASTAC] \|\|SPBC660.03c\|transcription factor TFIIF complex (beta subunit) (predicted)\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pombe041504.fasta] transcription initiation factor iif, beta subunit [Schizosaccharomyces pombe]gi\|4049502\|emb\|CAA22523.1\| SPBC660.03c [Schizosaccharomyces pombe]gi\|7801320\|emb\|CAB91188.1\| SPBC1198.13c [Schizosaccharomyces pombe]gi\|7493495\|pir\|\|T40615 transcription initi [nrdb_11152004_Chlamydomonas] \|tfg2\|SPBC660.03c\|transcription factor TFIIF complex \|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pompep2242005.fasta] (O94424) Transcription initiation factor IIF, beta subunit [pompep4896_normal_reversed] \|tfg2\|SPBC660.03c\|transcription factor TFIIF complex beta subunit Tfg2 \|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] Transcription initiation factor IIF subunit beta (ATP-dependent helicase TFG2) (TFIIF-beta) (TFIIF medium subunit) [nr-271106-contam.fasta] hypothetical protein SPBC1198.13c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] SPBC660.03c [Schizosaccharomyces pombe] [nr-271106-contam.fasta] SPBC1198.13c [Schizosaccharomyces pombe] [nr-271106-contam.fasta] Transcription initiation factor IIF subunit beta OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tfg2 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	307 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] spindle pole body [IDA] transcription factor TFIIF complex [ISS]
Biological Process:	regulation of transcription [IC] transcription initiation from RNA polymerase II promoter [ISS]
Molecular Function:	ATP binding [ISS] DNA binding [IEA] general RNA polymerase II transcription factor activity [ISS] ATP-dependent DNA helicase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEEKPTVRT EEDDRYEDDA GDLDLGQIGS RVWLVKIPKF LMDKWNSIPE DDAANLGCVR  60
   61 VKNDEIQLLL QNSPENADVP KIYNLRVMNK FVRNSYVFRE SETSSSMKST ALVGTVAHEC 120
  121 NVSPVINDDY RRVMQKRALA ASAPKRKVQM IDDRGGSLLA PGTLGSRSRS TTSFIRNVKP 180
  181 RTGEGLKNSR IPRNELLDIL FKCFEDYEYW TLKGLREYVK QPEVYLKEVL DSIAILNKRG 240
  241 PYALKYSLKP EYKGTMDAAS VELRNQQASQ SESSSIDHTG KNTSPDNPGT NAEEDEDDDG 300
  301 VEMIDVV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
general RNA polymerase II transcription factor activity	10.2797850053222	bayes_pls_golite062009
transcription initiation factor activity	6.22439849848084	bayes_pls_golite062009
RNA polymerase II transcription factor activity	4.06672086326535	bayes_pls_golite062009
transcription regulator activity	3.89911747857156	bayes_pls_golite062009
binding	2.17316238057078	bayes_pls_golite062009
transcription activator activity	2.12958061949296	bayes_pls_golite062009
protein binding	1.90482509358938	bayes_pls_golite062009
transcription coactivator activity	1.30173573105398	bayes_pls_golite062009
transcription factor binding	0.677361513203971	bayes_pls_golite062009
transcription cofactor activity	0.43974291826617	bayes_pls_golite062009
catalytic activity	0.304516551414824	bayes_pls_golite062009

Term	Confidence	Notes
general RNA polymerase II transcription factor activity	5.67074370996647	bayes_pls_golite062009
transcription regulator activity	5.55329976718261	bayes_pls_golite062009
DNA binding	5.08959163553491	bayes_pls_golite062009
nucleic acid binding	4.99681957904233	bayes_pls_golite062009
transcription factor activity	4.33152142980289	bayes_pls_golite062009
transcription activator activity	3.70589483230587	bayes_pls_golite062009
sequence-specific DNA binding	3.58179858678904	bayes_pls_golite062009
binding	3.52874320222492	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.60738445921725	bayes_pls_golite062009
transcription repressor activity	2.22485867684613	bayes_pls_golite062009
DNA-directed RNA polymerase activity	1.82365519759474	bayes_pls_golite062009
RNA polymerase activity	1.82365519759474	bayes_pls_golite062009
transcription elongation regulator activity	1.81270943531115	bayes_pls_golite062009
protein binding	1.80415286835431	bayes_pls_golite062009
RNA binding	0.992043085614693	bayes_pls_golite062009
transcription factor binding	0.85714789329232	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.66743181561551	bayes_pls_golite062009
nucleotidyltransferase activity	0.237727660028553	bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding	0.23177057841536	bayes_pls_golite062009
positive transcription elongation factor activity	0.13524243942225	bayes_pls_golite062009
structural molecule activity	0.111941063082739	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..125]	PSI-BLAST	28.522879	TFIIF beta subunit, Rap30
2	View Details	[126..307]	PSI-BLAST	27.69897	DNA-BINDING DOMAIN FROM HUMAN RAP30, NMR, MINIMIZED AVERAGE

Protein Overview: tfg2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: