YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: lys2

General Information:
Name(s) found: lys2 / SPAC343.16 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • homoaconitate hydratase Lys2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 721 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article][IMPLink to PubMed article]
    Biological Process: generation of precursor metabolites and energy [RCALink to PubMed article]
    glutamate metabolic process [RCALink to PubMed article]
    lysine biosynthetic process via aminoadipic acid [IMPLink to PubMed article]
    Molecular Function: iron ion binding [IEA]
    homoaconitate hydratase activity [IMPLink to PubMed article]
    4 iron, 4 sulfur cluster binding [IEA]
    iron-sulfur cluster binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSGEMHHPY QAFSKVGKCE ISQTNPSFSS GMRCLVRSAD IQFKGICGLT RGFASFNKPP  60
   61 QTITEKIVQK FAQNIPENKY VRSGDYVTIK PKHCMSHDNS WPVALKFMGI GAKKVFDNRQ 120
  121 IVCTLDHDVQ NKSEANLRKY KNIESFAKGQ GIDFYPAGRG IGHQIMVEQG YAMPGSMAVA 180
  181 SDSHSNTYGG VGCLGTPIVR TDAAAIWATG QTWWQIPPIA RVNLVGQLPK GLSGKDIIVS 240
  241 LCGAFNHDEV LNHAIEFYGE GLNSLSIESR LTIANMTTEW GALSGLFPTD EKLLAWYEDR 300
  301 LKFLGPNHPR VNRETLDAIK ASPILADEGA FYAKHLILDL STLSPAVSGP NSVKVYNSAA 360
  361 TLEKKDILIK KAYLVSCTNG RLSDIHDAAE TVKGKKVADG VEFYVGAASS EVEAAAQKNG 420
  421 DWQTLIDSGA RTLPAGCGPC IGLGTGLLKD GEVGISATNR NFKGRMGSRE ALAYLASPAV 480
  481 VAASAIAGKI VAPEGFKNAV SLVSAVDITD KVNKQTASKS STEAVDSETA IIDGFPSIVA 540
  541 GEIVFCDADN LNTDGIYPGR YTYRDDITKE EMAKVCMENY DSEFGKKTKK DDILVSGFNF 600
  601 GTGSSREQAA TAILSRGIPL VVGGSFSDIF KRNSINNALL AIQLPDLVQK LRTAFANESK 660
  661 ELTRRTGWHL KWDVRKSTVT VTTSDNKEMS WKIGELGNSV QSLFVRGGLE GWVKHEISKS 720
  721 N

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..721] PSI-BLAST 1000.0 STRUCTURE OF ACTIVATED ACONITASE. FORMATION OF THE (4FE-4S) CLUSTER IN THE CRYSTAL

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3-isopropylmalate dehydratase activity
    		•  11.6597692115322 bayes_pls_golite062009
  • aconitate hydratase activity
    		•  5.86356477922338 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.93956285477489 bayes_pls_golite062009
  • catalytic activity
    		•  2.4040324437254 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  2.08349115784849 bayes_pls_golite062009
  • hydro-lyase activity
    		•  2.04845291489052 bayes_pls_golite062009
  • lyase activity
    		•  2.0080619912194 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.67435647648998 bayes_pls_golite062009
  • binding
    		•  1.24981419049889 bayes_pls_golite062009
  • DNA binding
    		•  1.05282906893033 bayes_pls_golite062009
  • structural molecule activity
    		•  0.870913754566634 bayes_pls_golite062009
  • mRNA binding
    		•  0.52321922280827 bayes_pls_golite062009
  • RNA binding
    		•  0.41480744631042 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  0.239736179000069 bayes_pls_golite062009
  • metal cluster binding
    		•  0.239736179000069 bayes_pls_golite062009
  • protein binding
    		•  0.232638130896339 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle