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Protein Overview: SPBC14C8.15

General Information:
Name(s) found: SPBC14C8.15 [Sanger Pombe]
Description(s) found:
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  • pir||T39443 probable triglyceride lipase-cholesterol esterase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74676035|sp|O60095.1|TGCE3_SCHPO RecName: Full=Probable lipase C14C8.15 [NCBI NR]
  • gi|3006173|emb|CAA18432.1| triglyceride lipase-cholesterol esterase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112710|ref|NP_595918.1| triglyceride lipase-cholesterol esterase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • triglyceride lipase-cholesterol esterase [Sanger Pombe]
  • Probable lipase C14C8.15 OS=Schizosaccharomyces pombe GN=SPBC14C8.15 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE TRIGLYCERIDE LIPASE-CHOLESTEROL ESTERAS E: O60095; [pompepVF.fasta]
  • Putative triglyceride lipase-cholesterol esteras e [pompep4896]
  • |||putative triglyceride lipase-cholesterol esterase [pompepnew.fasta]
  • SPBC14C8.15 protein (EC 3.1.1.-) [4896.FASTAC]
  • |||triglyceride lipase-cholesterol esterase (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative triglyceride lipase-cholesterol esteras e [Schizosaccharomyces pombe]gi|3006173|emb|CAA18432.1| SPBC14C8.15 [Schizosaccharomyces pombe]gi|7493113|pir||T39443 probable triglyceride lipase-cholesterol esterase - fission yeast (Schizosaccharomyces [nrdb_11152004_Chlamydomonas]
  • |||triglyceride lipase-cholesterol esterase |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O60095) Putative triglyceride lipase-cholesterol esteras e [pompep4896_normal_reversed]
  • hypothetical protein SPBC14C8.15 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC14C8.15 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Probable lipase C14C8.15 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC14C8.15 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 460 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    integral to membrane [IEA]
    Golgi apparatus [IDALink to PubMed article]
    Biological Process: lipid metabolic process [ISSLink to PubMed article]
    cellular lipid catabolic process [ISS]
    sterol metabolic process [ISSLink to PubMed article]
    Molecular Function: lipase activity [ISSLink to PubMed article]
    sterol esterase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLNGNIMKY CLEKGEILIS FLLIALESMF RICTVILPSP LRNWFYEQSK KVYSYFLPEL  60
   61 LVDDNANKLT DARDTIDLCA LHGYDLEEHF VRTTDGYLLG LHRVYKKKKG KIEELNYLPP 120
  121 VLFIHGLMMN SESWVCNLKK EDAIPFALVE QGYDVWLGNL RGNKYSIKNI KFSSQNPKFW 180
  181 DFSLDSIAIF DIPSIVKYIL SVNSFDSISL VGFSQGAILA FAALSIDTEL RNSVRAFIAL 240
  241 APAIAPKKYS GRTVKSIIHA NSQLLYLMFG RNSMLGSAVF WQAVLYPPVF AKIVDLFLRF 300
  301 FLSWTGKNIS ETQKIVAYSH LYSFTSVKCF VHWAQITRRK VLQMYDDSPG FKPSYYTNLN 360
  361 RIARYPIENI RLPITLVYGS NDNMVDIETL KTQLPPLSQC IQIPNYEHLD IIMGDTKKDI 420
  421 VIQQVVEQLN HVIAGDYFES IKEEFGLDTE LVDGVMNHTI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..460] PSI-BLAST 61.522879 Gastric lipase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  3.20549979663539 bayes_pls_golite062009
  • palmitoyl-(protein) hydrolase activity
    		•  2.5858992959971 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  2.28093794718528 bayes_pls_golite062009
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • triglyceride lipase activity
    		•  1.2959733599348 bayes_pls_golite062009
  • sterol esterase activity
    		•  1.21262745914703 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  1.18565704009692 bayes_pls_golite062009
  • palmitoyl-CoA hydrolase activity
    		•  0.92549140936125 bayes_pls_golite062009
  • peptidase activity
    		•  0.858311047004898 bayes_pls_golite062009
  • lipase activity
    		•  0.849473630399459 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.81726006983431 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.590445773074315 bayes_pls_golite062009
  • carboxylesterase activity
    		•  0.424330502936163 bayes_pls_golite062009
  • binding
    		•  0.351031277062254 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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