Protein Overview: SPAC19G12.08

General Information:
Name(s) found:	SPAC19G12.08 [Sanger Pombe]
Description(s) found: Found 19 descriptions. SHOW ALL	fatty acid hydroxylase [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	347 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IC] membrane [ISS] integral to membrane [IEA] endoplasmic reticulum [IDA][ISS]
Biological Process:	fatty acid oxidation [IC] fatty acid metabolic process [ISS] sphingolipid metabolic process [ISS]
Molecular Function:	iron ion binding [IEA] sphingosine hydroxylase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASVTSEKCV ILSDGTEYDV TNYLVANKDA ADLLRRYHRQ EVADILNATS KSKHSEAVVE  60
   61 ILKSAKVPLK NKEFSDLVDQ NIGVGYGNEF IVKPTDLDKD FEKNHFLDLK KPLLPQILFG 120
  121 NIKKDVYLDQ VHRPRHYRGS GSAPLFGNFL EPLTKTPWYM IPLIWVPCVT YGFLYACTGI 180
  181 PFSVAITFFI IGLFTWTLVE YTMHRFLFHL DEYTPDHPIF LTMHFAFHGC HHFLPADKYR 240
  241 LVMPPALFLI FATPWYHFIQ LVLPHYIGVA GFSGAILGYV FYDLTHYFLH HRRMPNAYLT 300
  301 DLKTWHLDHH YKDYKSAYGI TSWFWDRVFG TEGPLFNEQG KISTKAK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..145]	PSI-BLAST	14.69897	Sulfite oxidase, C-terminal domain; Sulfite oxidase, N-terminal domain; Sulfite oxidase, middle catalytic domain
2	View Details	[146..347]	Pfam	17.136677	No description for PF04116.4 was found. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2.29500061324594	bayes_pls_golite062009
sphingosine hydroxylase activity	2.09152903381389	bayes_pls_golite062009
binding	1.13937274704645	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	1.05227276400356	bayes_pls_golite062009
cytochrome-c oxidase activity	0.973006556081137	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	0.973006556081137	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	0.973006556081137	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	0.888859895539844	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.808453086600089	bayes_pls_golite062009
electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity	0.754105021273961	bayes_pls_golite062009
heme-copper terminal oxidase activity	0.734823847983524	bayes_pls_golite062009
cation transmembrane transporter activity	0.602390039366203	bayes_pls_golite062009
oxidoreductase activity	0.583561246970036	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.493634303942328	bayes_pls_golite062009
protein binding	0.268795825133297	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.0873984825495362	bayes_pls_golite062009

2

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

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