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Protein Overview: mug30

General Information:
Name(s) found: mug30 / SPBP8B7.27 [Sanger Pombe]
Description(s) found:
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  • pir||T40821 probable ubiquitin-protein ligase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74582837|sp|O94275.1|MUG30_SCHPO RecName: Full=Probable E3 ubiquitin-protein ligase mug30; AltName: Full=Meiotically up-regulated gene 30 protein [NCBI NR]
  • gi|3810851|emb|CAA21812.1| ubiquitin-protein ligase E3 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113326|ref|NP_596534.1| ubiquitin-protein ligase E3 [Schizosaccharomyces pombe] [NCBI NR]
  • ubiquitin-protein ligase E3 [Sanger Pombe]
  • Probable E3 ubiquitin-protein ligase mug30 OS=Schizosaccharomyces pombe GN=mug30 PE=1 SV=1 [Swiss-Prot]
  • PUTATIVE UBIQUITIN-PROTEIN LIGASE: O94275; [pompepVF.fasta]
  • Putative ubiquitin-protein ligase [pompep4896]
  • |||ubiquitin-protein ligase (E3) [pompepnew.fasta]
  • SPBP8B7.27 protein [4896.FASTAC]
  • |||ubiquitin-protein ligase (E3)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative ubiquitin-protein ligase [Schizosaccharomyces pombe]gi|3810851|emb|CAA21812.1| SPBP8B7.27 [Schizosaccharomyces pombe]gi|7493143|pir||T40821 probable ubiquitin-protein ligase - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||ubiquitin-protein ligase |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O94275) Putative ubiquitin-protein ligase [pompep4896_normal_reversed]
  • |mug30||ubiquitin-protein ligase E3|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBP8B7.27 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBP8B7.27 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |mug30||ubiquitin-protein ligase E3 |Schizosaccharomyces pombe|chr 2|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Probable E3 ubiquitin-protein ligase mug30 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mug30 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 807 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cell division site [IDALink to PubMed article]
    cell tip [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    Biological Process: protein ubiquitination [RCALink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    small conjugating protein ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRPIEIANV SSGNRRTLPA LHGSSFSSRS ELDNNTNSKI SRRLRELVCQ RMGENPLRLR  60
   61 QSFHETISND SYGNSEKLVI RPCICCNSVL RYPAQAMCFR CSLCMTVNDV YFCLSGSQIK 120
  121 TKASTDGSQF ISVEHFVETI HQTRSALQLA KQRTGNVQAI VAAGLPLREL ISLVFGSPPI 180
  181 LNKLFSVKNG CSIQSSGLNY KLIYQLYHDI TNLDILITNE LLRAIESLLR RPMLYCHDPA 240
  241 DYQYLLILLE NPLLNSKSKN IVNKSSSILK RILGVLSNLN EKTHHFFISC FKKQPYNNPK 300
  301 FFRRKVDLIN KFIGQRLMET YSRNKRKHYY NNDWQIKSAA ITMALLYSAN SQMRLIDRSS 360
  361 FYCIMADFIN LYHDFELWEQ KINCFCFCQY PFLLSMGAKI SILQLDARRK MEIKAREAFF 420
  421 SSILSKMNVE PYLMIRVRRD RLLEDSLRQI NDRNKDFRKA LKVEFLGEEG IDAGGLKREW 480
  481 LLLLTRKVFS PEFGLFVNCE ESSNYLWFNY SHRSKEIDYY HMSGILMGIA IHNSINLDVQ 540
  541 MPRAFYKKLL QLPLSFNDLD DFQPSLYRGL KELLLFEGDV KNTYGLNFTI NLKAVEGFRT 600
  601 VELKEGGSEL SVDNENRKEY VLRYVDYLLN TTVKKQFSAF FDGFMKVCGG NAISLFQDNE 660
  661 ISKLIRGSEE VIDWELLKNV CVYDFYDQNA ISNSISESEP SMTASKYLCH SFVSKRKIIL 720
  721 WFWDLISHYS LKMQKLFLIF VTGSDRIPAT GAHNFQLRIS VLGPDSDQLP ISHTCFNHLC 780
  781 IWEYSSREKL KKKLDTALLE TNGFNIR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..122] FFAS03 1.06 CREB-binding transcriptional adaptor protein CBP (p300)
    2 View Details [123..233] MSA 3.076989 View MSA. No confident structure predictions are available.
    3 View Details [234..353] deduced N/A Confident ab initio structure predictions are available.
    4 View Details [354..807] PSI-BLAST 110.0 Ubiquitin-protein ligase E3a, Hect catalytic domain (E6ap)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.86664056933527 bayes_pls_golite062009
  • protein binding
    		•  0.519774392649288 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  7.14616396317218 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  6.99796579811325 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  6.03005793772151 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  4.50502148129705 bayes_pls_golite062009
  • sodium channel inhibitor activity
    		•  3.64966529121446 bayes_pls_golite062009
  • proline-rich region binding
    		•  3.26053533977534 bayes_pls_golite062009
  • phosphothreonine binding
    		•  2.3451206920409 bayes_pls_golite062009
  • phosphoserine binding
    		•  2.3451206920409 bayes_pls_golite062009
  • binding
    		•  2.32045312021486 bayes_pls_golite062009
  • ion channel inhibitor activity
    		•  2.14402963004533 bayes_pls_golite062009
  • channel inhibitor activity
    		•  2.14402963004533 bayes_pls_golite062009
  • RNA polymerase binding
    		•  1.8762146737407 bayes_pls_golite062009
  • ligase activity
    		•  1.85936914071714 bayes_pls_golite062009
  • protein binding
    		•  1.29390544644063 bayes_pls_golite062009
  • sodium channel regulator activity
    		•  1.19047973745862 bayes_pls_golite062009
  • catalytic activity
    		•  1.15152367676155 bayes_pls_golite062009
  • transcription factor binding
    		•  0.585725073778084 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.509776214744915 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.376852535152545 bayes_pls_golite062009
  • ubiquitin-ubiquitin ligase activity
    		•  0.373649200425601 bayes_pls_golite062009
  • DNA binding
    		•  0.187697131456126 bayes_pls_golite062009
  • channel regulator activity
    		•  0.072778668515899 bayes_pls_golite062009
    		• 0.051942165438844 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle