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Protein Overview: pus1

General Information:
Name(s) found: pus1 / SPCC126.03 [Sanger Pombe]
Description(s) found:
Found 22 descriptions.
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  • tRNA pseudouridylate synthase Lsp1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 534 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IGILink to PubMed article]
    Biological Process: pseudouridine synthesis [IEA]
    tRNA modification [IDALink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    RNA binding [IEA]
    pseudouridine synthase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRGGKRTWY NGDRREAKRN RPNSIYNGEG RPENLVVGEK KPKRKVACLV GYCGSGYHGM  60
   61 QLNPPSKTIE GDLFDAFVKA GAVSSYNADD PKKVALARAA RTDKGVHAAG NVISLKLIME 120
  121 DEKLIEKVNE HLPPSIRLWD VIRTINSFNP RTYCESRIYE YMVPTYAFVP PKPSSILGNC 180
  181 IMKNSPMPAE PINKENINQL SRSLFYEEGK EFWDDYDIAA KEILSLYEQD PEGFVNPYSK 240
  241 RGAAALANSE NNKGSEAGVS AKTNPDMDSD SSAIVNEFLK PDSVEDESAG SKIDPSYRLE 300
  301 RALKHIEVLK LKNYRISADR LSVIRETLNQ YVGVHNFHNF TVGQAFHQKN SNRVIRSFTA 360
  361 SDPFMIGDTE WISCKVHGQS FMLHQIRKMI ALAILVVRTG CPVERIQDAF KKTKINIPKG 420
  421 PGFGLLLESP FFKGYNEHKA PENNRDPIDF TKYEQKITAF KHAHIYDKIF LEEARKQVFH 480
  481 CFLSFIDSYN EEDFSYLSDI GITEKTQEVS SKLPDVLSSD EEEDSAENKD DLEG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..289] PSI-BLAST 72.0 No description for 2nqpA was found.
    2 View Details [290..438] FFAS03 4.92 No description for 1vs3A was found.
    3 View Details [439..534] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pseudouridine synthase activity
    		•  5.19957135839682 bayes_pls_golite062009
  • intramolecular transferase activity
    		•  3.78688422405974 bayes_pls_golite062009
  • isomerase activity
    		•  2.91720316078381 bayes_pls_golite062009
  • catalytic activity
    		•  2.02180970970004 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.21173188039059 bayes_pls_golite062009
  • DNA binding
    		•  0.950713703876672 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.909704702595901 bayes_pls_golite062009
  • binding
    		•  0.730744558777463 bayes_pls_golite062009
  • RNA binding
    		•  0.706879359688019 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle