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Protein Overview: vam6

General Information:
Name(s) found: vam6 / SPAC23H4.14 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • guanyl-nucleotide exchange factor Vma6 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 905 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    fungal-type vacuole membrane [ISS]
    cytosol [IDALink to PubMed article]
    fungal-type vacuole [ISS]
    extrinsic to membrane [IEA]
    HOPS complex [ISSLink to PubMed article]
    Biological Process: vesicle docking [ISSLink to PubMed article]
    regulation of catalytic activity [ICLink to PubMed article]
    vacuole fusion, non-autophagic [ISSLink to PubMed article]
    intracellular protein transport [IEA]
    Molecular Function: Rab guanyl-nucleotide exchange factor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRAFSLYRV LELSKARVEC VFELGGLVYV SNSNGDLDSY KIYNNEEEEA ADFVMEHVDV  60
   61 YPNFTKKPIT KVVSCATQDI FYALSDSQVY VYQISTFKKL FSFGAHCQNM CLYGDELIVL 120
  121 SSKKNLEIYE IQKNSKPNLT KTISLNDRPR SLAWVSPTMI LVSLSNDFCA VNTETSRISS 180
  181 LNLAWQQSSS LGLGISYIGM SIKSNKLHIT RISDDEVLLS KDSQGLLVNL KSLQVSRNPL 240
  241 RWPTVPQAVI YNSPYIITLH NQYIYIWNKE TYAMIQQIGI SNIYSTFSCH KNTFFTSNSY 300
  301 VWILTPEDFS NQIEALLNTE NLNEAISVLS QITVSQFPKR DYYLRITKRE KALRSFSSGD 360
  361 YDLAMRLFSE ISESPSTVLG LFPGLLDNNY SDAISILSMA PSQNESIESN VLFPGNHSNS 420
  421 QTDLRNGDAV STVANNKRLR SLSTYLTDSR RKANRFLSYD EEHYFLQKKN LFLNADGTLV 480
  481 AKEKLEKIAV QIDTTLFLIY MISSPALVGS LLRLPNRCET SVVETNLLSA KMYRELVEYY 540
  541 YGKSLHEAAL DLLTKLCDEP TDTLSLKGKS NTTSKYEPIL SYLEKLSPEL DHLIFKYSRV 600
  601 PLSEDPQNSI VIFIDENSEA STISKGVVLK YLETISYKVS IIYLEKLLLD NKFNDTVFPT 660
  661 RLALLYLKRI LELEETTDFK NQEVFKQTIE KLEDYLTNSK QYDANVVLQE INSQDEFLST 720
  721 VSIILYRRLS RHQDALDVYL KILNDWEGAL SYCNSVYSID GETEPYYMLL AEISKNYKSG 780
  781 SLNILDFITK YSSRLDLNRV FPLLPKNISM KSYHSLFSSQ FRQLFEELSN KETQSKLYQK 840
  841 RLEDLNEELT KVRSEKVVIT REKTCLFCHK RLGKSVISIF PDGSVVHYGC AKKYVSSNHL 900
  901 PYEAY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..288] FFAS03 1.24 No description for 2i3sA was found.
    2 View Details [289..905] PSI-BLAST 77.0 Clathrin D6 Coat

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.23598589443994 bayes_pls_golite062009
  • transporter activity
    		•  1.23232041140488 bayes_pls_golite062009
  • protein binding
    		•  1.16796757764458 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.750051725890322 bayes_pls_golite062009
  • hydrolase activity
    		•  0.346903609858078 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.271959658140432 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0560845588891794 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0245411309982146 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle