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Protein Overview: dcp2

General Information:
Name(s) found: dcp2 / SPAC19A8.12 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • mRNA decapping complex subunit Dcp2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 741 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    mRNA cap binding complex [IDALink to PubMed article][IGILink to PubMed article]
    cytoplasm [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasmic mRNA processing body [IGILink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [IGILink to PubMed article]
    deadenylation-independent decapping of nuclear-transcribed mRNA [ISSLink to PubMed article]
    deadenylation-dependent decapping of nuclear-transcribed mRNA [ISSLink to PubMed article]
    mRNA processing [RCALink to PubMed article]
    Molecular Function: magnesium ion binding [TASLink to PubMed article]
    ATP binding [IEA]
    RNA 7-methylguanosine cap binding [IGILink to PubMed article]
    protein binding [IPILink to PubMed article]
    manganese ion binding [IEA]
    m7G(5')pppN diphosphatase activity [IDALink to PubMed article][IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFTNATFSQ VLDDLSARFI LNLPAEEQSS VERLCFQIEQ AHWFYEDFIR AQNDQLPSLG  60
   61 LRVFSAKLFA HCPLLWKWSK VHEEAFDDFL RYKTRIPVRG AIMLDMSMQQ CVLVKGWKAS 120
  121 SGWGFPKGKI DKDESDVDCA IREVYEETGF DCSSRINPNE FIDMTIRGQN VRLYIIPGIS 180
  181 LDTRFESRTR KEISKIEWHN LMDLPTFKKN KPQTMKNKFY MVIPFLAPLK KWIKKRNIAN 240
  241 NTTKEKNISV DVDADASSQL LSLLKSSTAP SDLATPQPST FPQPPVESHS SFDIKQKILH 300
  301 LLNEGNEPKS PIQLPPVSNL PLNPPIQSSN SRLSHDNNSF DPFAYLGLDP KNPSASFPRV 360
  361 VSQNNMLTNK PVLNNHFQQS MYSNLLKDQN SVQHLFAASD MPSPMELPSP STVYHQVFYP 420
  421 PTSTSVSSYG LGKTPQPAYG SSSPYVNGHQ TQQISSLPPF QSQTQFLARN SDNSGQSYNS 480
  481 EGDSNSKRLL SMLSQQDTTP SSSTLSKEAN VQLANLFLTP NSLETKKFSD NSQGEEISDN 540
  541 LHGESCNNPN ANSVHSAQLL QALLHPSATE TKEETPKKTS DSLSLLTLLK SGLPTPANDL 600
  601 QNKSQNNERK ASSQVKELEV KNYSKSTDLL KKTLRIPRND EPLEAANQFD LLKVSPQQKS 660
  661 EVPPKRNELS QSKLKNRKKK ENSETNKNHV DMSPGFVKIL KRSPLADQKK EDTQESDFKG 720
  721 SDDHFLSYLQ SVVSSNSNGL H

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..241] PSI-BLAST 104.0 Crystal structure of S.pombe mRNA decapping enzyme Dcp2p
    2 View Details [242..335] deduced N/A No confident structure predictions are available.
    3 View Details [336..476] MSA 2.270994 View MSA. No confident structure predictions are available.
    4 View Details [477..617] deduced N/A Confident ab initio structure predictions are available.
    5 View Details [618..741] MSA 2.248993 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle