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Protein Overview: taf4

General Information:
Name(s) found: taf4 / SPAC23G3.09 [Sanger Pombe]
Description(s) found:
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  • gi|74638749|sp|Q9P7S4.1|TAF4_SCHPO RecName: Full=Transcription initiation factor TFIID subunit 4; AltName: Full=TBP-associated factor 4 [NCBI NR]
  • gi|6912026|emb|CAB72234.1| transcription factor TFIID complex subunit Taf4 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114021|ref|NP_593109.1| transcription factor TFIID complex subunit Taf4 [Schizosaccharomyces pombe] [NCBI NR]
  • pir||T50183 mpt1 like-protein [imported] - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • transcription factor TFIID complex subunit Taf4 [Sanger Pombe]
  • Transcription initiation factor TFIID subunit 4 OS=Schizosaccharomyces pombe GN=taf4 PE=2 SV=1 [Swiss-Prot]
  • COMPONENT OF RNA POLYMERASE II GENERAL TRANSCRIPTION FACTOR TFIID BY SIMILAR TO S. CEREVISIAE MPT1: Q9P7S4; [pompepVF.fasta]
  • COMPONENT OF RNA POLYMERASE II GENERAL TRANSCRIPTION FACTOR TFIID BY SIMILARITY TO YEAST MPT1: Q9P7S4; [pompepV13]
  • Similar to yeast mpt1 like-protein, possible involvement in transcription [pompep4896]
  • |||putative RNA polymerase II general transcription factor TFIID component [pompepnew.fasta]
  • SPAC23G3.09 protein [4896.FASTAC]
  • |taf4||transcription factor TFIID complex|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • similar to yeast mpt1 like-protein; possible involvement in transcription [Schizosaccharomyces pombe]gi|6912026|emb|CAB72234.1| SPAC23G3.09 [Schizosaccharomyces pombe]gi|11359200|pir||T50183 mpt1 like-protein [imported] - fission yeast (Schizosaccharom [nrdb_11152004_Chlamydomonas]
  • (Q9P7S4) Similar to yeast mpt1 like-protein, possible involvement in transcription [pompep4896_normal_reversed]
  • |taf4||transcription factor TFIID complex subunit Taf4 |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC23G3.09 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC23G3.09 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Transcription initiation factor TFIID subunit 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=taf4 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 365 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    transcription factor TFIID complex [ISSLink to PubMed article]
    chromatin [RCALink to PubMed article]
    Biological Process: RNA polymerase II transcriptional preinitiation complex assembly [ISS]
    positive regulation of transcription [ICLink to PubMed article]
    regulation of transcription [ICLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [ISSLink to PubMed article]
    Molecular Function: transcription initiation factor activity [ISSLink to PubMed article]
    RNA polymerase II transcription factor activity [ISSLink to PubMed article]
    general RNA polymerase II transcription factor activity [IC]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLNNPPSKR FGDDDDIPAN KRPKNEEYPE IPGYLGNRKP SYTQNPNSGP GKLHYASPRP  60
   61 NNVSSSVGVA SGGDRQEADQ LQDALISCGI QLKEEELNLS TSFYDPSSLN TFALTTEDRS 120
  121 RKSDFLNSFV LMQTVSNIVN LHRLKSMDSD IHALISMAVR DYLANLLQKM IVESHHRTSQ 180
  181 LHTDNYKQVD NVRQTLANFA YKEYESEERR RTVLNIRRAE HEARLAELNS ASTNEEGSSR 240
  241 RRKEQSSSAA AKNISEDAQN RMTNATASIM AGSALPSGGK KYSWMATDMT PMTPAVGGGF 300
  301 GIRKKDSNSL KPSSRDGVLP LQQEEKGIIT IRDALAVLEM DREGAGRIFG RGAKAMMRAY 360
  361 IRLKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..123] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [124..275] PSI-BLAST 19.221849 TAF(II)-135, (TAF(II)-130, hTAF4), histone fold domain
    3 View Details [276..365] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  9.25279783093877 bayes_pls_golite062009
  • DNA binding
    		•  4.49118409263799 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.35201412176948 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.08606081850613 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  3.96621818094279 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.28941584139552 bayes_pls_golite062009
  • binding
    		•  3.27510691458843 bayes_pls_golite062009
  • transcription factor activity
    		•  2.51581622888695 bayes_pls_golite062009
  • transcription activator activity
    		•  1.25487495162413 bayes_pls_golite062009
  • transcription factor binding
    		•  1.15204005455906 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.1297723528047 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.10331930589736 bayes_pls_golite062009
  • protein binding
    		•  1.07873333188144 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.01502031330902 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.72554769377984 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0852726470007639 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0792897588268993 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.0736756545988504 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle