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Protein Overview: skp1

General Information:
Name(s) found: skp1 / SPBC409.05 [Sanger Pombe]
Description(s) found:
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  • gi|74626243|sp|Q9Y709.1|SKP1_SCHPO RecName: Full=Suppressor of kinetochore protein 1; AltName: Full=P19/Skp1 homolog [NCBI NR]
  • gi|5731913|emb|CAB52607.1| SCF ubiquitin ligase complex subunit Skp1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|5001553|gb|AAD37024.1|AF071066_1 Skp1 homolog protein [Schizosaccharomyces pombe] [NCBI NR]
  • gi|4887603|dbj|BAA77790.1| p19/Skp1 homolog [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112247|ref|NP_595455.1| SCF ubiquitin ligase complex subunit Skp1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|15054484|dbj|BAB62325.1| skp1 [Schizosaccharomyces pombe] [NCBI NR]
  • pir||T45459 skp1 homolog - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • SCF ubiquitin ligase complex subunit Skp1 [Sanger Pombe]
  • Suppressor of kinetochore protein 1 OS=Schizosaccharomyces pombe GN=skp1 PE=1 SV=1 [Swiss-Prot]
  • ESSENTIAL; REQUIRED FOR DEGRADATION OF CIG2; SIMILAR TO S. CEREVISIAE SKP1; SKP1 FAMILY: Q9Y709; [pompepVF.fasta]
  • ESSENTIAL PROTEIN; REQUIRED FOR DEGRADATION OF CIG2; PUTATIVE YEAST SKP1 HOMOLOG; SKP1 FAMILY: Q9Y709; [pompepV13]
  • Essential for viability (SKP1) [pompep4896]
  • |skp1|psh1, sph1|putative serine/threonine protein kinase [pompepnew.fasta]
  • Skp1 (Psh1 protein) (Sph1 protein) (Spbc409.05 protein) [4896.FASTAC]
  • |skp1|psh1, sph1|SCF ubiquitin ligase complex (PMID 9990507)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • |skp1|psh1, sph1|SCF ubiquitin ligase complex |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • putative yeast skp1 homolog; skp1 family [Schizosaccharomyces pombe]gi|5001553|gb|AAD37024.1| Skp1 homolog protein [Schizosaccharomyces pombe]gi|5731913|emb|CAB52607.1| SPBC409.05 [Schizosaccharomyces pombe]gi|11291714|pir||T45459 skp1 homolog - fissio [nrdb_11152004_Chlamydomonas]
  • (Q9Y709) Essential for viability (SKP1) [pompep4896_normal_reversed]
  • |skp1|psh1, sph1|SCF ubiquitin ligase complex subunit Skp1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SCF ubiquitin ligase complex (PMID 9990507); essential; similar to S. cerevisiae YDR328C; skp1 family [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • skp1 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • ubiquitin ligase protein [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • p19/Skp1 homolog [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Skp1 homolog protein [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Suppressor of kinetochore protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=skp1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 161 amino acids

    Gene Ontology:
    Cellular Component: RAVE complex [IPILink to PubMed article]
    nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    SCF ubiquitin ligase complex [IDALink to PubMed article]
    Biological Process: regulation of proton-transporting ATPase activity, rotational mechanism [TASLink to PubMed article]
    mitotic cell cycle G2/M transition DNA damage checkpoint [IMPLink to PubMed article]
    vacuolar proton-transporting V-type ATPase complex assembly [TASLink to PubMed article]
    nuclear envelope organization [IMPLink to PubMed article]
    response to drug [IGILink to PubMed article]
    negative regulation of mitotic metaphase/anaphase transition [IMPLink to PubMed article]
    cytokinetic cell separation [IMPLink to PubMed article]
    vacuolar acidification [ISSLink to PubMed article]
    protein ubiquitination during ubiquitin-dependent protein catabolic process [ICLink to PubMed article]
    regulation of mitotic cell cycle [IGILink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed articleLink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKIKLISSD NEEFVVDQLI AERSMLIKNM LEDVGEINVP IPLPNVSSNV LRKVLEWCEH  60
   61 HKNDLYSGTE EESDIRLKKS TDIDEWDRKF MAVDQEMLFE IVLASNYLDI KPLLDTGCKT 120
  121 VANMIRGKSP EDIRKTFNIP NDFTPEEEEQ IRKENEWAED R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..161] PSI-BLAST 64.69897 Cyclin A/CDK2-associated p45, Skp1


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle