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Protein Overview: thi5

General Information:
Name(s) found: thi5 / SPBP8B7.30c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • transcription factor Thi5 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 857 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [ISSLink to PubMed article]
    negative regulation of conjugation with cellular fusion [IMPLink to PubMed article]
    regulation of ascospore formation [IGILink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [RCALink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [IGILink to PubMed article]
    Molecular Function: DNA binding [ISSLink to PubMed article]
    transcription factor activity [ISSLink to PubMed article]
    zinc ion binding [ISSLink to PubMed article]
    specific RNA polymerase II transcription factor activity [RCALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCPSDFSSRS LFLEAKEEEY KQRRRVPLDS RRRVRRACLS CRAKKIRCSG SEPCQACIAT  60
   61 PSQCKYADSL KERTPSKQFI AELSQRQKCF EYLMELLCPS LPHDTRSLVK LCKHVESSLA 120
  121 SGSDVRSLLI PGSIDQSVLK VAATNNKDDS SAVKSANVSF PSSSTPPSSD SNFSSIQNTD 180
  181 LNTSIKFTEN ISANAIHVNQ DKVIRSANNL IINSQPILPV RSFLDALGEP IYLSPTSSTY 240
  241 FLNSVLASLQ LNSSNTPESL LIDYQSKIPE DLSSSLLPLE LNTLQSTPTS VSVGSASSQG 300
  301 THEYSIINLT SNHSSFSLKA LKKIAHNLLP PVSVAERYAN EFFLRYQSFF YFYPPSVFSN 360
  361 RYQILADGLV NSDTLDTGFL AVALLIVVLG HFSNNNINVL PKEVQLSHID SMIQISEQLI 420
  421 SSLLNRCTLS SIQAVFLLSL YHFLTGNFKC AYSYLGFAIH SAHTLGLEHG STDNSTLNEV 480
  481 STEETSIRIC WSLRVLASFL YIQSGITPII NLFPNGLNSL KLPTVVPELE ARHLPSSVFH 540
  541 FVAIIKYAEI SVRSLNSLYE SSSDYLMDVS NFPKLLLKVE RIYSQARNWK LNLTHQQLNG 600
  601 TNDTSDLLFH SNVSLHLFYH YLIVKVSCPI MFFYLNNWYS VKPSSFTKGL NNKPSLEDVF 660
  661 SNLETCYESA KAIVQLSSKL LSAGQMDKCF YLEFEILYCS AIVLFLFSVM HLGAENPLLE 720
  721 SIYLLEDMGS RTIDSKVRLE KLKSAIEIFD INSATEMPIN EPLSASFESV NKENSQSGYM 780
  781 AWQNWVTELS SSNIPLGHAL GNPESNNSSN SFKPSHPSQS FLVNESLDFS SNPKEPPFLP 840
  841 WSEALLNMDM QLNRLGP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..97] PSI-BLAST 6.522879 PUT3
    2 View Details [98..256] FFAS03 2.32 PPR1
    3 View Details [257..349] deduced N/A Confident ab initio structure predictions are available.
    4 View Details [350..522] Pfam 19.0 No description for PF04082.9 was found. No confident structure predictions are available.
    5 View Details [523..606] deduced N/A No confident structure predictions are available.
    6 View Details [607..857] MSA 2.387994 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  4.56444258780502 bayes_pls_golite062009
  • DNA binding
    		•  4.26146437716972 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.17369933547911 bayes_pls_golite062009
  • transcription factor activity
    		•  3.049435548132 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.98081393153291 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.93914501897006 bayes_pls_golite062009
  • binding
    		•  2.91929847152301 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  2.44382866473054 bayes_pls_golite062009
  • transcription activator activity
    		•  2.24483536326713 bayes_pls_golite062009
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  4.34861813464065 bayes_pls_golite062009
  • DNA binding
    		•  4.03985756894684 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.97978190843512 bayes_pls_golite062009
  • transcription factor activity
    		•  2.87348461329489 bayes_pls_golite062009
  • binding
    		•  2.82809978070212 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.77469997789536 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.70904317608141 bayes_pls_golite062009
  • transcription activator activity
    		•  2.1512787242583 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  2.08956709478484 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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