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Protein Overview: taf73

General Information:
Name(s) found: taf73 / SPBC15D4.14 [Sanger Pombe]
Description(s) found:
Found 23 descriptions.
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  • TATA-binding protein associated factor [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 642 amino acids

    Gene Ontology:
    Cellular Component: transcription factor TFIID complex [TASLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: regulation of mitotic metaphase/anaphase transition [IGILink to PubMed article]
    positive regulation of transcription [ICLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [TASLink to PubMed article]
    Molecular Function: transcription initiation factor activity [ICLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQSSYSSGN STSDLNKIVL DYLFKKGYSR TEAMLRLEIS SVGAIPEEQQ DWHIGASETY  60
   61 VQVYILLRDW IDGTLDLYKP KLQKVLYPIF VHSYLDLLQK NDPEMAIYFF ESFRIEHEVL 120
  121 HGYDIRALAQ LKIASDVEEI EIAQLYRKNK YRINFTRSTF DLLVQFLFEN EVNGSGIIIR 180
  181 LLNQYIDIKI TMPQVEGKED PNVQAVYEMD EAKNEQTIIS EQEGIPGHSE QLLDYNKQSI 240
  241 QLGLRPLSEE VVTTLKNLLE VKDKDVEGRN EALNKILHPA KNLVELLTEK ENLINESTLE 300
  301 SPSDPPLPPT KMKDIDYFVS LLESEQNSLI LGKNATDPSV FMYTMHNTLS AVNCAAFSDD 360
  361 ASMFALGCAD SSIHLYSSTN NGPQPLVGSQ NEPLQKSSLI GHTRPVFGVS ISPQKEFILS 420
  421 CSEDGFTRLW SKDTKSTIVK YAGHNAPIWD VQFSPFGYYF ATASHDQTAR LWDVEHAAPL 480
  481 RVFVGHQNDV DCVSFHPNAA YLATGSSDHT TRMWDVRTGG TVRVFNAHHS PVSALCMSAD 540
  541 GLSLASADES GIIKVWDLRS SNQHVSFVKH SSIVYSLSFS YDNKILVSGG ADTDVNFWDL 600
  601 TYRNNLSDGE QSPLLFNFKT KNTIIQNLSF TRRNYCLALS SS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..74] deduced N/A No confident structure predictions are available.
    2 View Details [75..224] PSI-BLAST 18.221849 No description for 2j49A was found.
    3 View Details [225..642] PSI-BLAST 74.0 PAF-AH Holoenzyme: Lis1/Alfa2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
    		• 6.67009948605948 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  5.61142954750278 bayes_pls_golite062009
  • actin binding
    		•  3.86142918698875 bayes_pls_golite062009
  • acetyltransferase activity
    		•  3.85374902981345 bayes_pls_golite062009
  • RNA binding
    		•  3.77273677738815 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.35098520158193 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.31615347567536 bayes_pls_golite062009
  • GTPase activity
    		•  3.23750443966606 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.14917998298348 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.1056443224755 bayes_pls_golite062009
  • tubulin binding
    		•  2.76945430061825 bayes_pls_golite062009
  • microtubule binding
    		•  2.72684103222924 bayes_pls_golite062009
  • dynein binding
    		•  2.54821997913979 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.3610959773142 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.30918780727915 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  2.28847626309518 bayes_pls_golite062009
  • snoRNA binding
    		•  2.27164613239345 bayes_pls_golite062009
  • protein binding
    		•  2.26925404328312 bayes_pls_golite062009
  • actin filament binding
    		•  2.0735069176589 bayes_pls_golite062009
  • dynactin binding
    		•  1.85146647785657 bayes_pls_golite062009
  • DNA binding
    		•  1.71685536470455 bayes_pls_golite062009
  • structural molecule activity
    		•  1.47097979074281 bayes_pls_golite062009
  • transcription activator activity
    		•  1.23969853550045 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • receptor activity
    		•  1.12819778129653 bayes_pls_golite062009
  • transcription factor activity
    		•  1.08768505897883 bayes_pls_golite062009
  • mRNA binding
    		•  1.05053985350578 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  1.01166033978052 bayes_pls_golite062009
  • myosin binding
    		•  0.989691178611801 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • signal transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • protein transporter activity
    		•  0.964340340346761 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.734793983890004 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.676924760416604 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.658573452658359 bayes_pls_golite062009
  • transcription factor binding
    		•  0.489473003915035 bayes_pls_golite062009
  • dynein intermediate chain binding
    		•  0.443846546939402 bayes_pls_golite062009
  • insulin receptor binding
    		•  0.43316396073854 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.426429095658617 bayes_pls_golite062009
  • kinase activity
    		•  0.387572734234845 bayes_pls_golite062009
  • myosin II binding
    		•  0.33142771724387 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  0.311523647180993 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30761651528651 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.28606552120995 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  0.251120087240234 bayes_pls_golite062009
  • myosin heavy chain kinase activity
    		•  0.231534552000461 bayes_pls_golite062009
  • protein kinase activity
    		•  0.229242350006544 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.226335610368636 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.182612389752591 bayes_pls_golite062009
  • chromatin binding
    		•  0.151977098745772 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.118975415284669 bayes_pls_golite062009
  • receptor binding
    		•  0.0390635451962911 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle