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Protein Overview: pex1

General Information:
Name(s) found: pex1 / SPCC553.03 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • AAA family ATPase Pex1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 937 amino acids

    Gene Ontology:
    Cellular Component: peroxisome [ISSLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: peroxisome organization [ISSLink to PubMed article]
    organelle organization [NAS]
    Molecular Function: ATPase activity [ISSLink to PubMed article]
    ATP binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRCIVSYKSL RSCLVNVPEL LLESISEPVQ NYAVQAVVCK NDIKKTFYFG ISGIPSQFSF  60
   61 EIDSTYAHTL KLAENQEINL SIIDCTHEIE QLEIEPVTSN DWEIAERNAA WLEENLLVQY 120
  121 RVATTERFII YLPSGTFIQF QPLKLIPSSL CGRLLRTTEV LITPKPNTSA IEVKENRKVN 180
  181 LRCVVENRLL PDSVTADSPA LCVFLPLNFP DRPDVVYMDG GNLKSTIVCQ CVSCPFQIPG 240
  241 HFFISKSLAL SYSIKTGFKF QIWKAHNPPS SSKFILEQKG LPPESNLSSE LVAAKLKNSY 300
  301 LMDGMTLKLV DIAVSYSVSG LSGVVKNPIQ DIKITSDTNV PVNAGIRNNS PRLSMQPFPH 360
  361 EFAQVRNAVF LHQNIYINGP KGCGKSNLVH SLFDYYSLNS IYFQMIVSCS EIDRSSFAKF 420
  421 QSFWNNVFIQ AERYEPSIIY LDDVHCLISS SNENGELGFV EEREIAFLQH QIINLKRKRK 480
  481 IIFIGFGEEF LTFSENLVLP LLFQIKIALP SLAVTRRKEI LTTIFQENFS DITMDSIEFI 540
  541 SVKTEGYLMT DLVLFVKRLL SEAFVEKIQN GPKHLMNKGL IEKTLKDFVP LQLRKAKFVK 600
  601 SSIRWIDIAG MQEAKEAVRD IIESPVKYSL IYKQCRLRLP TGILLFGYPG CGKTYLASAI 660
  661 SSTFPVQFIS IKGPELLDKY IGKSEQGVRD LFSRAQMAKP CVLFFDEFDS VAPRRGQDST 720
  721 GVTDRVVNQI LTQMDGAESL DGVYIVAATT RPDMIDPALL RPGRLDKLIF CDLPNEEERL 780
  781 EVLQKLANRF HIENAAMLKK LSTLTDGYTY ADLSSLLYDA HLIAVHKLLK RVSINAVDPS 840
  841 QTTSSFTNLT TESKRNASML ALPPESRYNQ NMQSMSDSKS VVIEDYMLME ALKKNSPSLN 900
  901 SEEFEHLSNL YRDFRSKLFE PELNARNTDV GSKTRQI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..171] PSI-BLAST 35.30103 Structure of the N-terminal domain of PEX1 AAA-ATPase: Characterization of a putative adaptor-binding domain
    2 View Details [172..937] PSI-BLAST 135.0 VCP/p97

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  3.79320034972587 bayes_pls_golite062009
  • syntaxin binding
    		•  3.07307576313813 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.66565132432505 bayes_pls_golite062009
  • binding
    		•  1.64221234725269 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.59966904665651 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.5827346030945 bayes_pls_golite062009
  • ATPase activity
    		•  1.58256263495768 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.58037625997232 bayes_pls_golite062009
  • SNARE binding
    		•  1.16366125009416 bayes_pls_golite062009
  • catalytic activity
    		•  0.767627914425245 bayes_pls_golite062009
  • protein binding
    		•  0.634982583867058 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  0.533025271192252 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle