YRC Public Data Repository - Protein Structure Prediction

Protein:	pex1
Organism:	Schizosaccharomyces pombe
Length:	937 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pex1.

Description	E-value	Query Range	Subject Range
CDC48_SOYBN - Cell division cycle protein 48 homolog OS=Glycine max GN=CDC48 PE=2 SV=1	505.0	[0..164]	[918..6]
gi\|215704352, gi... - gi\|215704711\|dbj\|BAG94339.1\| unnamed protein product [Oryza sativa Japonica Group], gi\|215704637\|dbj... gi\|125542437 - gi\|125542437\|gb\|EAY88576.1\| hypothetical protein OsI_10049 [Oryza sativa Indica Group]	497.0	[0..172]	[918..16]
CDC48_CAPAN - Cell division cycle protein 48 homolog OS=Capsicum annuum GN=CAFP PE=2 SV=1	497.0	[0..164]	[918..6]
CD48E_ARATH - Cell division control protein 48 homolog E OS=Arabidopsis thaliana GN=CDC48E PE=1 SV=2	495.0	[0..162]	[918..3]
gi\|49527427 - gi\|49527427\|emb\|CAG61067.1\| unnamed protein product [Candida glabrata] gi\|50291367, gi\|... - gi\|50291367\|ref\|XP_448116.1\| unnamed protein product [Candida glabrata], gi\|49527427\|emb\|CAG61067.1\|...	495.0	[0..154]	[918..1]
gi\|98962497 - gi\|98962497\|gb\|ABF59516.1\| putative spindle disassembly related protein CDC48 [Nicotiana tabacum]	495.0	[0..164]	[918..6]

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Predicted Domain #1

Region A:
Residues: [1-171]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRCIVSYKSL RSCLVNVPEL LLESISEPVQ NYAVQAVVCK NDIKKTFYFG ISGIPSQFSF  60
   61 EIDSTYAHTL KLAENQEINL SIIDCTHEIE QLEIEPVTSN DWEIAERNAA WLEENLLVQY 120
  121 RVATTERFII YLPSGTFIQF QPLKLIPSSL CGRLLRTTEV LITPKPNTSA I

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.30103
Match:	1wlfA
Description:	Structure of the N-terminal domain of PEX1 AAA-ATPase: Characterization of a putative adaptor-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	3.79320034972587	bayes_pls_golite062009
syntaxin binding	3.07307576313813	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.66565132432505	bayes_pls_golite062009
binding	1.64221234725269	bayes_pls_golite062009
pyrophosphatase activity	1.59966904665651	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.5827346030945	bayes_pls_golite062009
ATPase activity	1.58256263495768	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.58037625997232	bayes_pls_golite062009
SNARE binding	1.16366125009416	bayes_pls_golite062009
catalytic activity	0.767627914425245	bayes_pls_golite062009
protein binding	0.634982583867058	bayes_pls_golite062009
ATPase activity, coupled	0.533025271192252	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [172-937]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVKENRKVNL RCVVENRLLP DSVTADSPAL CVFLPLNFPD RPDVVYMDGG NLKSTIVCQC  60
   61 VSCPFQIPGH FFISKSLALS YSIKTGFKFQ IWKAHNPPSS SKFILEQKGL PPESNLSSEL 120
  121 VAAKLKNSYL MDGMTLKLVD IAVSYSVSGL SGVVKNPIQD IKITSDTNVP VNAGIRNNSP 180
  181 RLSMQPFPHE FAQVRNAVFL HQNIYINGPK GCGKSNLVHS LFDYYSLNSI YFQMIVSCSE 240
  241 IDRSSFAKFQ SFWNNVFIQA ERYEPSIIYL DDVHCLISSS NENGELGFVE EREIAFLQHQ 300
  301 IINLKRKRKI IFIGFGEEFL TFSENLVLPL LFQIKIALPS LAVTRRKEIL TTIFQENFSD 360
  361 ITMDSIEFIS VKTEGYLMTD LVLFVKRLLS EAFVEKIQNG PKHLMNKGLI EKTLKDFVPL 420
  421 QLRKAKFVKS SIRWIDIAGM QEAKEAVRDI IESPVKYSLI YKQCRLRLPT GILLFGYPGC 480
  481 GKTYLASAIS STFPVQFISI KGPELLDKYI GKSEQGVRDL FSRAQMAKPC VLFFDEFDSV 540
  541 APRRGQDSTG VTDRVVNQIL TQMDGAESLD GVYIVAATTR PDMIDPALLR PGRLDKLIFC 600
  601 DLPNEEERLE VLQKLANRFH IENAAMLKKL STLTDGYTYA DLSSLLYDAH LIAVHKLLKR 660
  661 VSINAVDPSQ TTSSFTNLTT ESKRNASMLA LPPESRYNQN MQSMSDSKSV VIEDYMLMEA 720
  721 LKKNSPSLNS EEFEHLSNLY RDFRSKLFEP ELNARNTDVG SKTRQI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	135.0
Match:	1oz4A
Description:	VCP/p97
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: