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Protein Overview: dpb4

General Information:
Name(s) found: dpb4 / SPBC3D6.09 [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • DNA polymerase epsilon subunit Dpb4 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 210 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    nuclear chromatin [IDALink to PubMed article]
    DNA replication preinitiation complex [IC]
    nuclear replication fork [ICLink to PubMed article]
    cytosol [IDALink to PubMed article]
    epsilon DNA polymerase complex [IPILink to PubMed article]
    Biological Process: DNA replication initiation [IGILink to PubMed article]
    Molecular Function: DNA binding [IEA]
    DNA-directed DNA polymerase activity [TASLink to PubMed article]
    protein binding [IPILink to PubMed article]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQDKSKETS ELDDLALPRS IIMRLVKGVL PEKSLVQKEA LKAMINSATL FVSFLTSASG  60
   61 EIATNNNRKI LMPQDVLNAL DEIEYPEFSK TLKKHLEAYE LALKEKRLKL PNVSDVDNRK 120
  121 KAKIDAHDTT PLDEEKDELE EERIAEDIAQ NEVEQNIDDV EDLEEVNDTL DANAESPQIE 180
  181 TIHLTDATGN PIEDSSESDS EESLQLNDSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..210] PSI-BLAST 26.522879 Negative cofactor 2, NC2, beta chain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA-directed DNA polymerase activity
    		•  7.30463919195401 bayes_pls_golite062009
  • DNA polymerase activity
    		•  7.25909396656216 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  4.91761894051618 bayes_pls_golite062009
  • DNA binding
    		•  3.33590750206299 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.33150991098513 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.74104602193943 bayes_pls_golite062009
  • binding
    		•  2.68226682911828 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.18081531032351 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.71814239259767 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.71244156762178 bayes_pls_golite062009
  • transferase activity
    		•  1.4922191078713 bayes_pls_golite062009
  • transcription factor activity
    		•  1.43258372806556 bayes_pls_golite062009
  • transcription activator activity
    		•  0.56890094816403 bayes_pls_golite062009
  • transcription factor binding
    		•  0.48055497002898 bayes_pls_golite062009
  • protein binding
    		•  0.38229791767081 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.36684586697198 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.0502944474168801 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle